AI Article Synopsis

  • In India, there are significant treatment gaps in mental healthcare for low- and middle-income populations, particularly affecting those with severe mental disorders who struggle to recover due to inadequate infrastructure and care standards in psychiatric hospitals.
  • The SITAR study is a randomized controlled trial aiming to evaluate the effects of psychiatric hospital reforms and personalized recovery plans on the outcomes of psychosis patients aged 18-60, focusing on disability, symptom severity, and quality of life, with 100 participants in each study arm.
  • The study seeks to promote human rights and dignity in mental healthcare reform, with ethical approval obtained to ensure that findings will aid in improving institutional care practices.

Article Abstract

Introduction: Low-income and middle-income settings like India have large treatment gaps in mental healthcare. People with severe mental disorders face impediments to their clinical and functional recovery, and have large unmet needs. The infrastructure and standards of care are poor in colonial period psychiatric hospitals, with no clear pathways to discharge and successfully integrate recovered individuals into the community. Our aim is to study the impact of psychiatric hospital reform on individual patient outcomes in a psychiatric hospital in India.

Methods And Analysis: Structured Individualised inTervention And Recovery (SITAR) is a two-arm pragmatic randomised controlled trial, focusing on patients aged 18-60 years with a hospital stay of 12-120 months and a primary diagnosis of psychosis. It tests the effectiveness of structural and process reform with and without an individually tailored recovery plan on patient outcomes of disability (primary outcome WHO Disability Assessment Scale), symptom severity, social and occupational functioning and quality of life. A computer-generated permuted block randomisation schedule will allocate recruited subjects to the two study arms. We aim to recruit 100 people into each trial arm. Baseline and outcome measures will be undertaken by trained researchers independent to the case managers providing the individual intervention. A health economic analysis will determine the costing of implementing the individually tailored recovery plan.

Ethics And Dissemination: The study will provide answers to important questions around the nature and process of reforms in institutional care that promote recovery while being cognizant of protecting human rights, and dignity. Ethical approval for SITAR was obtained from a registered ethics committee in India (Institutional Ethics Committee VikasAnvesh Foundation, VAF/2018-19/012 dated 6 December 2018) and the University of Warwick's Biomedical and Scientific Research Ethics Committee (REGO-2019-2332, dated 21 March 2019), and registered on the Central Trial Registry of India (CTRI/2019/01/017267). Trial results will be published in accordance to CONSORT guidelines.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228526PMC
http://dx.doi.org/10.1136/bmjopen-2019-035753DOI Listing

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