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Signal Transduction: Physical Deformation of the Membrane Activates Integrins. | LitMetric

Signal Transduction: Physical Deformation of the Membrane Activates Integrins.

Curr Biol

Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0726, USA. Electronic address:

Published: May 2020

AI Article Synopsis

Article Abstract

New work describes a novel mechanism of mechanotransduction, whereby force-induced membrane deformation activates integrins by disrupting the association of the transmembrane domains of α and β integrins.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cub.2020.02.068DOI Listing

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