AI Article Synopsis
- Centrosomes help establish the front and back (anterior-posterior polarization) in the one-cell embryo of C. elegans, leading to the separation of different cell types.
- New research by De Henau et al. highlights that mitochondria play a role in this symmetry-breaking process.
- Mitochondria contribute by generating hydrogen peroxide at the posterior end of the egg, influencing cell development.
Article Abstract
Centrosomes break symmetry in the C. elegans one-cell embryo, triggering its anterior-posterior polarization and initiating segregation of somatic and germline cell lineages. In this issue of Developmental Cell, De Henau et al. show that mitochondria also contribute to symmetry breaking by producing hydrogen peroxide at the egg's future posterior pole.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233474 | PMC |
| http://dx.doi.org/10.1016/j.devcel.2020.04.007 | DOI Listing |
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