Characterization of the novel HLA-DQB1*03:01:46 variant allele in a French hematopoietic stem cell donor.

HLA

Department of Biology and Therapies, Histocompatibility Laboratory, Etablissement Français du sang Auvergne-Rhône-Alpes, Grenoble, France.

Published: September 2020

HLA-DQB1*03:01:46 is a variant of the HLA-DQB1*03:01:01:01 gene.
The difference between the two variants is due to a single nucleotide substitution.
This substitution occurs specifically at codon 142.3 in exon 3 of the gene.

HLA-DQB1*03:01:46 differs from HLA-DQB1*03:01:01:01 by one nucleotide substitution at codon 142.3 in exon 3.

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http://dx.doi.org/10.1111/tan.13921	DOI Listing

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