Developing renewable and sustainable energy sources is a compelling goal in materials science and engineering. In particular, natural photosynthesis with its infinite energy reservoir provides profound inspiration for energy conversion and storage systems. Here, we report a multiplex living solar cell that offers a drastic power enhancement by harnessing the broadband spectra of the visible wavelength range for photosynthesis. Cyanobacteria are embedded into a nanostructural complex composed of Au nanoparticles (NPs) and ZnO nanorods (NRs). This nanocomposite system is capable of not only generating excitons but also amplifying the photosynthetic performance of the cell via a far-field scattering effect in the broadband region of the light, resulting in multiplex energy harvesting with a peak power density of 6.15 mW/m. We envision that this study will provide a strategic way to enhance the performance of biophotovoltaics, enabling efficient and durable energy generation.
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http://dx.doi.org/10.1021/acs.nanolett.0c00894 | DOI Listing |
Lancet Microbe
December 2024
Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, NC, USA. Electronic address:
Background: Serology for dengue viruses (DENV) and Zika virus (ZIKV) has been hindered by antibody cross-reactivity, which limits the utility of these tests for surveillance and assessment of sero-status. Our aim was to develop a multiplexed IgG-based assay with increased accuracy to assess the history of previous DENV and ZIKV infections.
Methods: We developed and assessed the analytical performance of a sample-sparing, multiplexed, microsphere-based serological assay using domain III of the envelope protein (EDIII) of DENV serotypes 1-4 and ZIKV, the most variable region between each virus.
Mol Syst Biol
December 2024
Cell Signaling Laboratory, Department of Oncology, University College London Cancer Institute Paul O'Gorman Building, University College London, London, WC1E 6BT, UK.
Technical limitations have prevented understanding of how growth factor signals are encoded in distinct activity patterns of the phosphoinositide 3-kinase (PI3K)/AKT pathway, and how this is altered by oncogenic pathway mutations. We introduce a kinetic, single-cell framework for precise calculations of PI3K-specific information transfer for different growth factors. This features live-cell imaging of PI3K/AKT activity reporters and multiplexed CyTOF measurements of PI3K/AKT and RAS/ERK signaling markers over time.
View Article and Find Full Text PDFACS Nano
December 2024
Department of Biomedical Engineering, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.
Preclinical and clinical diagnostics depend greatly on medical imaging, which enables the identification of physiological and pathological processes in living subjects. It is often necessary to use contrast agents to complement anatomical data with functional information or to describe the disease phenotypically. Nanomaterials are used as contrast agents in many advanced bioimaging techniques and applications because of their high payload, physicochemical properties, improved sensitivity, and multimodality.
View Article and Find Full Text PDFACS Sens
December 2024
Key Laboratory of Biomedical Information Engineering of Ministry of Education, Xi'an Jiaotong University, Xi'an 710049, China.
Detections of internal substances and morphologies for label-free living cells are crucial for revealing malignant diseases. With the phase serving as a coupling of refractive index (RI) (marker for substances) and thickness (morphology), existing decoupling methods mainly rely on complex integrated systems or extensive optical field information. Developing simple and rapid decoupling methods remains a challenge.
View Article and Find Full Text PDFNpj Flex Electron
February 2024
Institute for Health Innovation and Technology, National University of Singapore, Singapore 117599, Singapore.
Wireless and battery-free radio-frequency (RF) sensors can be used to create physical spaces that ambiently sense and respond to human activities. Making such sensors ultra-flexible and transparent is important to preserve the aesthetics of living environments, accommodate daily activities, and functionally integrate with objects. However, existing RF sensors are unable to simultaneously achieve high transparency, flexibility, and the electrical conductivity required for remote room-scale operation.
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