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Rapid optical determination of salivary cortisol responses in individuals undergoing physiological and psychological stress.
Sci Rep
December 2024
Research Centre for Biomedical Engineering (RCBE), School of Science and Technology, City, University of London, Northampton Square, London, EC1V 0HB, UK.
Traditional methods for management of mental illnesses in the post-pandemic setting can be inaccessible for many individuals due to a multitude of reasons, including financial stresses and anxieties surrounding face-to-face interventions. The use of a point-of-care tool for self-management of stress levels and mental health status is the natural trajectory towards creating solutions for one of the primary contributors to the global burden of disease. Notably, cortisol is the main stress hormone and a key logical indicator of hypothalamic-pituitary adrenal (HPA) axis activity that governs the activation of the human stress system.
View Article and Find Full Text PDFMulti-environment and multi-parameter screening of stability and coating efficiency of gold nanoparticle bioconjugates in application media.
Sci Rep
December 2024
Department of Chemistry G. Ciamician, University of Bologna, Bologna, 40126, Italy.
Gold nanoparticles (AuNPs) and their biocompatible conjugates find wide use as transducers in (bio)sensors and as Nano-pharmaceutics. The study of the interaction between AuNPs and proteins in representative application media helps to better understand their intrinsic behaviors. A multi-environment, multi-parameter screening strategy is proposed based on asymmetric flow field flow fractionation (AF4)-multidetector.
View Article and Find Full Text PDFminimally invasive surgery is the surgery of the present and has become the "gold standard" for the most pathologies. The training of surgeons in minimally invasive techniques is mandatory required to be carried out during the residency program. In Romania, there is no national minimally invasive surgical training program, only universities and certain university hospitals are concerned with this aspect.
View Article and Find Full Text PDFStem cell therapy approaches for non-malignant diseases & non-haematological diseases in India: A systematic review.
Indian J Med Res
November 2024
Department of Pediatrics, All India Institute of Medical Sciences, Patna, India.
Background & objectives Our study aims to provide the diversity of stem cell use for non-malignant, non-haematological diseases in India through the lens of clinical trials. Methods A PRISMA approach was used to evaluate the safety and efficacy of stem cell use for the period 2001-2021 in India. The outcomes were measured using each disease category, types of stem cells, the origin of stem cells, safety, and efficacy.
View Article and Find Full Text PDFValidation of parental screening tool S-PMV11: Convergent validity with Bayley-III in assessing developmental functioning.
Neuro Endocrinol Lett
December 2024
Department of Psychological Sciences, Faculty of Social Sciences and Health Care, Constantine the Philosopher University in Nitra, Slovakia.
Background: With the increasing use of developmental screening tools, there is a growing need to validate parental screening methods for the early detection of developmental difficulties in children, regarding their psychometric properties.
Methods: This study evaluates the convergent validity of the S-PMV11 parental screening tool by comparing its outcomes with the Bayley Scales of Infant and Toddler Development (Bayley-III), the gold standard for direct assessment.
Results: We analyzed data from 30 children and found significant correlations between S-PMV11 scores and Bayley-III assessments across cognitive, language, and motor skill domains.
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