First Reported Case of Extramedullary Plasmacytoma of the Appendix.

Gastroenterology Res

Department of Pathology and Laboratory Medicine, University of California Irvine (UCI) Medical Center, Orange, CA 92868, USA.

Published: April 2020

AI Article Synopsis

  • An extramedullary plasmacytoma in the gastrointestinal tract is a very rare condition, and this case report discusses one that occurred in the appendix of a 35-year-old man.
  • The patient experienced upper abdominal pain and a CT scan revealed a small mass at the tip of the appendix.
  • Diagnosis was confirmed through microscopic examination, showing abnormal plasma cells, and it's noted that this is the first documented case of an appendiceal extramedullary plasmacytoma.

Article Abstract

An extramedullary plasmacytoma involving the gastrointestinal tract is extremely rare. We report an appendiceal extramedullary plasmacytoma in a 35-year-old man who presented to the emergency department because of upper abdominal pain. Computed tomography (CT) imaging revealed an incidental mass (3.7 × 1.9 × 1.6 cm) at the tip of the appendix. Microscopically, the appendix, periappendiceal soft tissue, and nearby lymph nodes were diffusely infiltrated by plasma cells that were kappa light chain restricted. Subsequent workup included an unremarkable bone marrow biopsy, as well as urine and serum electrophoresis. A diagnosis of kappa-restricted solitary extramedullary plasmacytoma was made. To our knowledge, this is the first case reported of an appendiceal extramedullary plasmacytoma in the medical literature.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188365PMC
http://dx.doi.org/10.14740/gr1277DOI Listing

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