Objectives: Older people are often socially deprived, which may predispose them to frailty. The aim of the study was to identify the independent effects of social deficits and their combined effects with frailty ("social frailty") in predicting functional decline, institutionalization, and mortality in older adults living in the community.
Design: Longitudinal study with a 3-year follow-up.
Setting And Participants: A nationally representative sample of community-dwelling older people aged 65 years or older in South Korea (N = 11,241).
Methods: Social deficits were defined as deficiencies in socioeconomic status, living situation, social network size, contact with social networks, social support, and social activities. The number of social deficits was categorized as none (0), low (1-2), and high (3 or more), based on the summated score. Frailty status was defined using the Fried criteria. Cox proportional hazards model was used to analyze the effects of the increasing levels of social deficits on functional decline, institutionalization, and mortality. The combined effects of both social deficits and physical frailty were also assessed, controlling for covariates.
Results: The prevalence of frailty was 7.7%, with 49.1% being prefrail at baseline. Overall, the presence of social deficits tended to elevate the risk of adverse outcomes, where acquiring 1 social deficit was associated with an 11% to 27% increase in their risks. In the multivariable analysis, those with a high level of social deficits demonstrated a significantly elevated mortality risk [hazard ratio (HR) = 1.45, 95% confidence interval (CI): 1.07, 1.97). There was a trend toward increasing hazards when social deficits were combined with physical frailty, with the group having a high level of social deficits and being frail exhibiting the highest mortality risk (HR = 3.14, 95% CI: 1.81, 5.46).
Conclusions And Implications: Social adversity independently predicted mortality. When combined with physical frailty, an accumulation of social deficits increased the predictive value.
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http://dx.doi.org/10.1016/j.jamda.2020.03.010 | DOI Listing |
NPJ Digit Med
January 2025
Technology & Innovation Hub, Shirley Ryan AbilityLab, Chicago, IL, USA.
Early screening and evaluation of infant motor development are crucial for detecting motor deficits and enabling timely interventions. Traditional clinical assessments are often subjective, without fully capturing infants' "real-world" behavior. This has sparked interest in portable, low-cost technologies to objectively and precisely measure infant motion at home, with a goal of enhancing ecological validity.
View Article and Find Full Text PDFSci Rep
January 2025
Business School, Hebei University of Economics and Business, Shijiazhuang, 050062, China.
The development and implementation of county carbon control action plans in the Yellow River Basin (YRB) are crucial for realizing the "dual carbon" goals and modernizing national governance. Utilizing remote sensing data from 2001 to 2020, this study constructs a light-carbon conversion model and a carbon footprint model to simulate the carbon footprint of county energy consumption in the YRB. Employing spatial autocorrelation and spatial Durbin models, the study examines the temporal-spatial evolution characteristics and spatial effect mechanism.
View Article and Find Full Text PDFJ Autism Dev Disord
January 2025
Department of Psychology, University of Alabama at Birmingham, AL, Birmingham, USA.
Purpose: Prior research demonstrates that children with autism are more likely to experience unintentional injuries than the general population. Limited research exists on the symptoms or traits directly related to autism and this elevated injury rate, especially from the perspective of families with children with autism. This study used qualitative methodology to elucidate risk factors that may contribute to unintentional injuries in children with autism from the perspective of mothers raising children with autism.
View Article and Find Full Text PDFEur J Neurosci
January 2025
European Brain Council, Brussels, Belgium.
Good brain health plays a significant role in an individual's well-being and profoundly impacts the collective economy and society. Brain development does not stop at birth, and some aspects continue throughout childhood and adolescence, allowing the full development of cognitive functions. Different determinants related to physical health, healthy environments, safety and security, life-long learning and social connection as well as access to quality services influence the way our brains develop, adapt and respond to stress and adversity.
View Article and Find Full Text PDFCurr Pharm Des
January 2025
Director Operations and Medical Writing, RYT Lifesciences Pvt Ltd, Ahmedabad, Gujrat, India.
Objective: This study aimed to evaluate the effectiveness and safety of Altibrain® in combination with standard Autism Spectrum Disorder (ASD) treatment compared to standard ASD treatment alone in individuals diagnosed with ASD.
Method: A randomized, open-label trial was conducted involving 120 participants aged 3 to 17 years, randomly assigned to either the Standard ASD Treatment group or the Altibrain® + Standard ASD Treatment group. Sixty patients were randomly allocated to each Standard ASD Treatment group or the Altibrain® + Standard ASD Treatment group.
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