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This study aims to determine the factors associated with mortality and neurodevelopmental morbidity in patients with Maple Syrup Urine Disease (MSUD) seen at a tertiary hospital in the Philippines during a 10-year period. The medical records of patients diagnosed with MSUD seen at Philippine General Hospital (PGH) from 2010 to 2019 were reviewed. Socioeconomic, healthcare, and clinical factors were determined.
View Article and Find Full Text PDFA pilot study of the utility of a hospital-based school program for pediatric patients with cardiac diagnoses.
Front Pediatr
December 2024
Marian University College of Osteopathic Medicine, Indianapolis, IN, United States.
Introduction: Pediatric patients with complex cardiac diagnoses are at increased risk for physical, cognitive, and developmental complications. Formalized school support [i.e.
View Article and Find Full Text PDFEEG-based brain age prediction in infants-toddlers: Implications for early detection of neurodevelopmental disorders.
Dev Cogn Neurosci
December 2024
Developmental Medicine, Boston Children's Hospital, 300 Longwood Avenue, Boston, 02115, MA, USA; Harvard Medical School, 25 Shattuck St, Boston, 02115, MA, USA. Electronic address:
The infant brain undergoes rapid developmental changes in the first three years of life. Understanding these changes through the prediction of chronological age using neuroimaging can provide insights into typical and atypical brain development. We utilized 938 resting-state EEG recordings from 457 typically developing infants, 2 to 38 months old, to develop age prediction models.
View Article and Find Full Text PDF"You go an extra mile": a qualitative study of community health worker perspectives in a health promotion intervention in urban South Africa.
BMC Health Serv Res
December 2024
SAMRC/Wits Developmental Pathways for Health Research Unit, Department of Paediatrics, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Background: As part of the Healthy Life Trajectories Initiative in South Africa, the Bukhali health promotion intervention is being implemented by community health workers (CHW's) with young women in urban Soweto. The perspectives of these CHW's have not been fully explored.
Methods: A qualitative study was conducted to describe CHW's perspectives and experiences of delivering the Bukhali intervention.
Variable and slow-paced neural dynamics in HVC underlie plastic song production in juvenile zebra finches.
BMC Neurosci
December 2024
Max Planck Institute for Biological Intelligence, Eberhard-Gwinner-Str., 82319, Seewiesen, Germany.
Zebra finches undergo a gradual refinement of their vocalizations, transitioning from variable juvenile songs to the stereotyped song of adulthood. To investigate the neural mechanisms underlying song crystallization-a critical phase in this developmental process-we performed intracellular recordings in HVC (a premotor nucleus essential for song learning and production) of juvenile birds. We then compared these recordings to previously published electrophysiological data from adult birds.
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