Getting started: altering promoter choice as a mechanism for cell type differentiation.

Genes Dev

Department of Molecular Biology, Cellular Biology, and Biochemistry, Brown University, Providence, Rhode Island 02912, USA.

Published: May 2020

AI Article Synopsis

  • Lu and colleagues explore a new mechanism of alternate promoter choice that plays a crucial role in the differentiation of spermatocytes.
  • This research suggests that promoter choice could be an important mechanism in the differentiation processes of various cell types, beyond just spermatocytes.
  • The findings are discussed in detail on pages 663-677 of the issue, highlighting their significance in understanding cellular differentiation.

Article Abstract

In this issue of , Lu and colleagues (pp. 663-677) have discovered a key new mechanism of alternative promoter choice that is involved in differentiation of spermatocytes. Promoter choice has strong potential as mechanism for differentiation of many different cell types.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197355PMC
http://dx.doi.org/10.1101/gad.338723.120DOI Listing

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