We present a system developed to premagnetize liquid samples in an ultra-low-field nuclear magnetic resonance experiment. Liquid samples of a few milliliters are exposed to a magnetic field of about 70 mT, which is abruptly switched off, to leave a transverse microtesla field, where nuclei start precessing. An accurate characterization of the transients and intermediate field level enables a reliable operation of the detection system, which is based on an optical magnetometer.
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http://dx.doi.org/10.1063/5.0003882 | DOI Listing |
Nat Commun
August 2024
National Key Laboratory of Materials for Integrated Circuits, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050, People's Republic of China.
Investigating proton transport at the interface in an excited state facilitates the mechanistic investigation and utilization of nanomaterials. However, there is a lack of suitable tools for in-situ and interfacial analysis. Here we addresses this gap by in-situ observing the proton transport of graphene quantum dots (GQDs) in an excited state through reduction of magnetic resonance relaxation time.
View Article and Find Full Text PDFChemphyschem
October 2023
University of North Carolina at Chapel Hill, Chapel Hill, NC, U.S.
Ultra-low field nuclear magnetic resonance spectroscopy (NMR) and imaging (MRI) inherently suffer from a low signal-to-noise ratio due to the small thermal polarization of nuclear spins. Transfer of polarization from a pre-polarized spin system to a thermally polarized spin system via the Spin Polarization Induced Nuclear Overhauser Effect (SPINOE) could potentially be used to overcome this limitation. SPINOE is particularly advantageous at ultra-low magnetic field, where the transferred polarization can be several orders of magnitude higher than thermal polarization.
View Article and Find Full Text PDFPLoS One
May 2023
Department of Neuroscience, Imaging and Clinical Sciences, G. D'Annunzio University of Chieti and Pescara, Chieti, CH, Italy.
Purpose: Recently, new MRI systems working at magnetic field below 10 mT (Very and Ultra Low Field regime) have been developed, showing improved T1-contrast in projected 2D maps (i.e. images without slice selection).
View Article and Find Full Text PDFJ Magn Reson
March 2023
Univ. Bordeaux, CNRS, CRMSB, UMR 5536, F-33000 Bordeaux, France. Electronic address:
Development of very-low field MRI is an active area of research. It aims at reducing operating costs and improve portability. However, the signal-to-noise issue becomes prominent at ultra-low field (<1 mT), especially for molecular imaging purposes that addresses specific biochemical events.
View Article and Find Full Text PDFSens Actuators B Chem
June 2021
State Key Laboratory of Functional Materials of Informatics, Shanghai Institute of Microsystem and Information Technology (SIMIT), Chinese Academy of Sciences, Shanghai, 200050, PR China.
The rapid and sensitive diagnosis of the highly contagious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is one of the crucial issues at the outbreak of the ongoing global pandemic that has no valid cure. Here, we propose a SARS-CoV-2 antibody conjugated magnetic graphene quantum dots (GQDs)-based magnetic relaxation switch (MRSw) that specifically recognizes the SARS-CoV-2. The probe of MRSw can be directly mixed with the test sample in a fully sealed vial without sample pretreatment, which largely reduces the testers' risk of infection during the operation.
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