Pituitary-derived bovine growth hormone (bGH) was administered to six lactating Friesland ewes for 7 d. There was no consistent galactopoietic response, with changes in milk yield varying from 0 to 33% during treatment compared with the pretreatment period. The major effect of bGH on the concentration of milk constituents was to increase fat by 14.2% (P less than 0.05). Treatment resulted in significant increases in arterial plasma concentrations of growth hormone, insulin-like growth factor I and glucose, with decreases in the plasma arterial concentrations of acetate and certain amino acids. There was a marked reduction in haematocrit and in haemoglobin concentration which took at least 3 d to recover. The arterio-venous difference across the mammary gland decreased for O2 during treatment and the veno-arterial difference for CO2 decreased after treatment. Mammary respiratory quotient therefore decreased significantly after bGH treatment. The results suggest that bGH exerts effects at a number of separate loci.
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http://dx.doi.org/10.1017/s0022029900033240 | DOI Listing |
Orphanet J Rare Dis
December 2024
Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Background: Meier-Gorlin syndrome (MGORS) is a rare autosomal inherited form of primordial dwarfism. Pathogenic variants in 13 genes involved in DNA replication initiation have been identified in this disease, but homozygous intronic variants have never been reported. Additionally, whether growth hormone (GH) treatment can increase the height of children with MGORS is unclear.
View Article and Find Full Text PDFBMC Vet Res
January 2025
Department of Animal Production, Faculty of Agriculture, Mansoura University, Mansoura, 35516, Egypt.
Phytochemicals have been effectively used to enhance the growth and productivity of farm animals, while the potential roles of essential oils and their nano-emulsions are limited. This plan was proposed to investigate the impacts of orally administered moringa oil (MO) or its nano-emulsion (NMO) on the growth, physiological response, blood health, semen attributes, and sperm antioxidant-related genes in rams. A total of 15 growing Rahmani rams were enrolled in this study and allotted into three groups.
View Article and Find Full Text PDFBMC Plant Biol
January 2025
Research Institute of Tropical Forestry, Chinese Academy of Forestry, Guangzhou, 520521, China.
Background: Calmodulin-binding transcription activator (CAMTA) proteins play significant roles in signal transduction, growth and development, as well as abiotic stress responses, in plants. Understanding their involvement in the low-temperature stress response of teak is vital for revealing cold resistance mechanisms.
Results: Through bioinformatics analysis, the CAMTA gene family in teak was examined, and six CAMTA genes were identified in teak.
Diabetes Technol Ther
January 2025
Department of Paediatric Diabetes and Endocrinology, John Hunter Children's Hospital, New Lambton Heights, New South Wales, Australia.
To compare glycemic outcomes during and following moderate-intensity exercise (MIE), high-intensity interval exercise (HIE), and resistance exercise (RE) in adolescents with type 1 diabetes (T1D) using a hybrid closed-loop (HCL) insulin pump while measuring additional physiological signals associated with activity. Twenty-eight adolescents (average age 16.3 ± 2.
View Article and Find Full Text PDFEur J Med Genet
January 2025
Genetics Institute, Rambam Health Care Campus, Haifa, Israel; The Ruth and Bruce Rappaport Faculty of Medicine, The Technion, Haifa, Israel. Electronic address:
Background: Ulnar mammary syndrome (UMS) is an autosomal dominant disorder caused by heterozygous pathogenic variants in the T-box transcription factor 3 (TBX3) gene. The phenotype is classically characterized by upper limb defects and apocrine/mammary gland hypoplasia. Endocrine abnormalities include hypogonadotropic hypogonadism (HH), partial growth hormone deficiency and dysmorphic features, while ectopic pituitary gland and various congenital anomalies have also been described.
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