We study nonadiabatic effects of geometric pumping. With arbitrary choices of periodic control parameters, we go beyond the adiabatic approximation to obtain the exact pumping current. We find that a geometrical interpretation for the nontrivial part of the current is possible even in the nonadiabatic regime. The exact result allows us to find a smooth connection between the adiabatic Berry phase theory at low frequencies and the Floquet theory at high frequencies. We also study how to control the geometric current. Using the method of shortcuts to adiabaticity with the aid of an assisting field, we illustrate that it enhances the current.
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http://dx.doi.org/10.1103/PhysRevLett.124.150602 | DOI Listing |
Sci Rep
January 2025
College of Intelligent systems Science and Engineering, Harbin Engineering University, Harbin, 150006, China.
Most of toolpaths for machining is composed of series of short linear segments (G01 command), which limits the feedrate and machining quality. To generate a smooth machining path, a new optimization strategy is proposed to optimize the toolpath at the curvature level. First, the three essential components of optimization are introduced, and the local corner smoothness is converted into an optimization problem.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom.
Background: Early Onset Alzheimer's Disease (EOAD) is thought to result from a combination of environmental, genetic, and lifestyle factors. Herpesvirus infections may contribute to the development of EOAD and the objective of our study is to identify potential associations between herpes virus infections and the risk of developing EOAD.
Method: Amyloid-status Alzheimer's disease was diagnosed based on clinical history and ATN criteria, determined by the measuring the Amyloidß42:40 ratio, tau, and 181-Phospho-tau in the cerebrospinal fluid.
Alzheimers Dement
December 2024
Department of Neurosurgery, Maxine Dunitz Neurosurgical Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Background: This study identifies and quantifies diverse pathological tau forms in the retina at both early and advanced stages of Alzheimer's disease (AD) and assesses their correlation with disease status. In the pathogenesis of AD, the tau protein undergoes post-translational modifications, including hyperphosphorylation (p-tau). As the disease progresses, pathological tau can propagate as oligomers, aggregate into fibrils, and paired helical filaments (PHF), and ultimately form intraneuronal neurofibrillary tangles (NFTs).
View Article and Find Full Text PDFChemistry
January 2025
Indian Institute of Technology Kanpur, Department of Chemistry, Kanpur, 208016, Kanpur, INDIA.
Herein, we report the precise control of molecular to supramolecular chirality induction at the single-molecule level just upon subtle modification in an achiral 'nano-size' trizinc(II) porphyrin trimer. A slight variation in the projection of the substituent at the periphery of the central porphyrin unit in a porphyrin trimer (host) resulted in pronounced changes in the interchromophoric arrangement, leading to distinct 'open' and 'closed' conformations. While 'open' form generates 'monomeric' complex with low CD amplitude, 'closed' form produces exclusive 'polymer' with large, amplified CD signal with opposite sign due to stronger intermolecular excitonic coupling.
View Article and Find Full Text PDFNat Commun
January 2025
CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Modern Mechanics, CAS Center for Excellence in Complex System Mechanics, University of Science and Technology of China, Hefei, Anhui, China.
Control of crack propagation is crucial to make tougher heterogeneous materials. As a crack interacts with material heterogeneities, its front distorts and adopts complex tortuous configurations. While the behavior of smooth cracks with straight fronts in homogeneous materials is well understood, the toughening by rough cracks with tortuous fronts in heterogeneous materials remains unsolved.
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