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Similar Publications
Effects of advanced age upon astrocyte-specific responses to acute traumatic brain injury in mice.
J Neuroinflammation
April 2020
Sanders-Brown Center on Aging, University of Kentucky, Room 433, Sanders-Brown Bldg., 800 S. Limestone Street, Lexington, KY, 40536, USA.
Background: Older-age individuals are at the highest risk for disability from a traumatic brain injury (TBI). Astrocytes are the most numerous glia in the brain, necessary for brain function, yet there is little known about unique responses of astrocytes in the aged-brain following TBI.
Methods: Our approach examined astrocytes in young adult, 4-month-old, versus aged, 18-month-old mice, at 1, 3, and 7 days post-TBI.
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