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Surgical sharp debridement alongside maggot debridement therapy (MDT) for the treatment of diabetic foot ulcers (DFUs): A systematic review of case reports.
Surg Pract Sci
March 2025
Department of Nursing, Zanjan University of Medical Sciences, Zanjan, Iran.
Objective: The objective of this systematic review of case reports is to evaluate the efficacy and safety of combining surgical sharp debridement with maggot debridement therapy (MDT) for the treatment of diabetic foot ulcers (DFUs).
Methods: A comprehensive literature search was conducted across multiple databases, including PubMed, Embase, Cochrane Library, and Web of Science. Inclusion criteria were studies that reported on the use of surgical sharp debridement alongside MDT for DFUs, while exclusion criteria included insufficient detail on treatment methods or patient outcomes, non-human studies, and non-English publications.
Porcine pericardial decellularized matrix bilayer patch containing adipose stem cell-derived exosomes for the treatment of diabetic wounds.
Mater Today Bio
February 2025
Department of Plastic Surgery, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.
Chronic hard-to-heal wounds pose a significant threat to patients' health and quality of life, and their clinical management remains a challenge. Adipose-derived stem cell exosomes (ADSC-exos) have shown promising results in promoting diabetic wound healing. However, effectively enhancing the retention of exosomes in wounds for treatment remains a key issue that needs to be addressed.
View Article and Find Full Text PDFReal-Time Subcutaneous Arterial Navigation for Thinning of an Anterolateral Thigh Flap Using Photoacoustic Imaging and Projection Mapping: A Case Report.
Microsurgery
January 2025
Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Thinning of anterolateral thigh flap is challenging. Anatomical studies have shown variations in arterial branching patterns in the subcutaneous layer, which were suspected to be the reason for the high frequency of thinning failures. We attempted to visualize subcutaneous arterial courses preoperatively and perform thinning of perforator flaps using this information appropriately.
View Article and Find Full Text PDFThe infected diabetic foot: Incidence and risk factors for dehiscence after surgery for diabetic foot infections.
Wound Repair Regen
December 2024
Department of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Our objective was to assess the incidence, risk factors and clinical outcomes of dehiscence after foot surgery in diabetic patients. We used pooled patient-level data from two randomised clinical trials with 240 diabetic patients who required foot surgery for infections. Most patients (n = 180, 75.
View Article and Find Full Text PDFArticle Synopsis
- - The study aimed to assess how effective a gel with active oxygen is in preventing Medication-Related Osteonecrosis of the Jaw (MRONJ) in a rat model.
- - Twelve rats underwent surgery after receiving a drug (zoledronate) known to cause osteonecrosis and were divided into two groups: one treated with oxygen gel and the other left untreated.
- - Results showed that the untreated group had more severe MRONJ symptoms, suggesting that the gel may help in preventing this condition, although further research is needed due to the pilot nature of the study.
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