Objective: In this study we aimed to evaluate whether there is a link between circulating 25-OH-D levels and molecular response in chronic myeloid leukemia (CML).

Material And Method: A total of 61 patients with CML (31 women, 30 men) were recruited in this cross-sectional study.

Results: Binary logistic regression analysis demonstrated that increased vitamin D levels were independently associated with molecular response in subjects with CML.

Conclusion: Our results indicated for the first time in the literature that severe deficiency of vitamin D was independently associated with molecular unresponsiveness in subjects with CML. 25-OH-D may be contributing to molecular response in the patients (Tab. 3, Ref. 24).

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http://dx.doi.org/10.4149/BLL_2020_059DOI Listing

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