AI Article Synopsis
- The study aimed to evaluate the significance of the extracellular water/total body water (ECW/TBW) value in patients with chronic liver diseases (CLDs).
- Involved 552 CLD patients, the research assessed the relationship of the ECW/TBW value with liver fibrosis, nutritional status, and prognosis in cirrhotic patients.
- Findings revealed that higher ECW/TBW values were linked to worsening liver fibrosis, decreased muscle mass, and poorer prognosis for those with cirrhosis.
Article Abstract
Background/aim: A bioimpedance analysis (BIA) can indicate an overhydrated state as the extracellular water/total body water (ECW/TBW) value. This study aimed to assess the clinical significance of this value in patients with chronic liver diseases (CLDs).
Patients And Methods: A total of 552 CLD patients who received a liver biopsy and underwent anthropometric assessment and BIA-based body composition analysis were enrolled. The association of the ECW/TBW value with the liver fibrosis and nutritional status was assessed. The relationship between the ECW/TBW value and the prognosis of cirrhotic patients (N=209) was also evaluated.
Results: The ECW/TBW value increased as liver fibrosis progressed and was also related to decreased muscle mass/sarcopenia. The presence of overhydration was associated with a poor prognosis of cirrhotic patients.
Conclusion: An increased ECW/TBW value was associated with progressive liver fibrosis and malnutrition and related to the prognosis of cirrhotic patients.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279852 | PMC |
| http://dx.doi.org/10.21873/invivo.11912 | DOI Listing |
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