Human Rhinovirus/Enterovirus in Pediatric Acute Respiratory Distress Syndrome.

J Pediatr Intensive Care

Department of Pediatrics, Columbia University Medical Center, New York-Presbyterian Children's Hospital, New York, United States.

Published: June 2020

AI Article Synopsis

  • The study investigates the impact of human rhinovirus/enterovirus (HRV/HEV) on severe lower respiratory infections in children admitted to a pediatric intensive care unit (PICU).
  • Out of 155 children tested positive for HRV/HEV, 62% needed significant respiratory support within the first day of admission.
  • The research indicates that HRV/HEV is linked to serious respiratory issues, with 14% of these patients diagnosed with pediatric acute respiratory distress syndrome (ARDS).

Article Abstract

The role of human rhinovirus/enterovirus (HRV/HEV) in severe lower respiratory tract infections remains unclear. We characterized the respiratory status of children admitted to a large academic pediatric intensive care unit (PICU) who tested positive for only HRV/HEV. One hundred and fifty-five children met inclusion criteria with 62% requiring positive pressure respiratory support of 5 cm of water pressure or more within the first 24 hours of admission. Among them, 34% had SaO to FiO ratios of 264 or less with 22 patients (14%) meeting criteria for pediatric acute respiratory distress syndrome. HRV/HEV is associated with significant respiratory disease in children admitted to the PICU.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186013PMC
http://dx.doi.org/10.1055/s-0039-3400466DOI Listing

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