Charge transfer at P atoms in an N-heterocyclic carbene stabilized 6π-electron aromatic dicarbondiphosphide 1 has been observed upon interaction with a variety of small molecule substrates that feature a polar E-H bond (E = C, N, and O). As a result, these P atoms exhibit fleeting nucleophilicity and electrophilicity behaving as potential independent active sites, which effect the spontaneous addition of E-H bonds leading to a series of unsymmetrical 1,3-diphosphetane frameworks bearing P-C (2), P-N (6 and 7), and P-O bonds (8b, 8c, and 9). In addition, 1,3-diphosphetanium salts have been achieved when X-type substituents are weakly coordinating (i.e. [(CN)2CH]- (3), I- (4), and [(PhOH)2PhO]- (10)). The mechanisms of such transformations are investigated using density functional theory calculations.
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http://dx.doi.org/10.1039/d0dt01341b | DOI Listing |
Environ Health (Wash)
November 2024
Guangdong Provincial Key Laboratory of Environmental Pollution and Health, College of Environment and Climate, Jinan University, Guangzhou 510632, China.
Various contaminants are present in aquatic environment and pose potential threats to pelagic and benthic organisms, calling for effective risk assessment. Traditional risk assessments based on target analysis are useful when the principal contaminants responsible for ecological risk are known; however, these approaches become challenging when dealing with chemical mixtures. In addition, the compositions of chemical mixtures often differ in regions with different levels of socioeconomic development, requiring risk assessment methods that are applicable under different pollution scenarios.
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September 2024
College of Environmental Science and Engineering, Ministry of Education Key Laboratory of Pollution Processes and Environmental Criteria, Tianjin Key Laboratory of Environmental Remediation and Pollution Control, Nankai University, 38 Tongyan Rd., Tianjin 300350, People's Republic of China.
Cadmium-bearing nanoparticles, such as nanoparticulate cadmium selenide (CdSe) and cadmium sulfide (CdS), widely exist in the environment and originate from both natural and anthropogenic sources. Risk assessment of these nanoparticles cannot be accurate without taking into account the properties of the protein corona that is acquired by the nanoparticles upon biouptake. Here, we show that the compositions of the protein corona on CdSe/CdS nanoparticles are regulated collectively by the surface atomic arrangement of the nanoparticles and the abundance and distribution of cysteine moieties of the proteins in contact with the nanoparticles.
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October 2024
State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
Extreme high temperatures in the summer have become a global concern, and their risks to the inflammatory system have been largely unknown. Here we appraised the exposure risks of summer heatwaves by comparing the sera cytokine levels in healthy individuals under high and normal temperatures. In addition, we established a cell model with a 1.
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August 2024
School of Public Health, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Climate change has resulted in a marked increase in heat extremes that carry a severe risk for morbidity and mortality. Kidney is sensitive to heat stimulation, and acute kidney injury (AKI) is the early event. In this study, we investigated the adverse effects of heat extremes and their underlying mechanism.
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November 2023
Department of Environmental Health Sciences, School of Public Health, University of Michigan, Ann Arbor, Michigan 48109, United States.
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