AI Article Synopsis
- Central nervous system tumors pose a major challenge in modern medicine due to their complex location.
- MicroRNA (miRNA) plays a crucial role in cancer development and has been linked to various medical conditions since its discovery in the 1990s.
- Recent research highlights miRNA's involvement in critical cancer processes like tumor growth, blood vessel formation, cell death regulation, and treatment resistance, particularly in gliomas.
Article Abstract
Central nervous system tumors are a significant problem for modern medicine because of their location. The explanation of the importance of microRNA (miRNA) in the development of cancerous changes plays an important role in this respect. The first papers describing the presence of miRNA were published in the 1990s. The role of miRNA has been pointed out in many medical conditions such as kidney disease, diabetes, neurodegenerative disorder, arthritis and cancer. There are several miRNAs responsible for invasiveness, apoptosis, resistance to treatment, angiogenesis, proliferation and immunology, and many others. The research conducted in recent years analyzing this group of tumors has shown the important role of miRNA in the course of gliomagenesis. These particles seem to participate in many stages of the development of cancer processes, such as proliferation, angiogenesis, regulation of apoptosis or cell resistance to cytostatics.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246719 | PMC |
| http://dx.doi.org/10.3390/ijms21093046 | DOI Listing |
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