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The polychromatism of postmortem cerebrospinal fluid.
Forensic Sci Med Pathol
August 2024
Institute of Forensic Medicine, University of Wuerzburg, Versbacher Str. 3, 97078, Wuerzburg, Germany.
Based on the assumption that postmortem cerebrospinal fluid (CSF) is contaminated depending on the chosen sampling technique in the forensic setting resulting in bloody or at least hemolytic CSF samples, we systematically documented a total of 183 postmortem CSF samples. These samples were all assessed for their quality and color, regardless of the cause of death or the postmortem interval. The investigations were carried out through subjective assessment of color and turbidity, as well as objective measurements of the optical density (OD) of the CSF supernatants after centrifugation of each sample, with standardized photographic documentation.
View Article and Find Full Text PDFVisual inspection versus spectrophotometry for xanthochromia detection in patients with sudden onset severe headache-A diagnostic accuracy study.
Headache
August 2024
Department of Neurology, Nordland Hospital Trust, Bodø, Norway.
Objective: There is still disagreement about whether to routinely use spectrophotometry to detect xanthochromia in cerebrospinal fluid (CSF) or whether visual inspection is adequate. We aimed to evaluate the diagnostic accuracy of these methods in detecting an aneurysmal subarachnoid hemorrhage in patients with sudden onset severe headache.
Background: When a patient presents to the emergency department with a headache for which there is suspicion of a subarachnoid hemorrhage, the gold standard to rule this out is to perform a CSF analysis for xanthochromia with or without spectrophotometry if the cranial non-contrast computed tomography (CT) upon admission is negative.
Community-Acquired Meningitis Complicated With Pyogenic Ventriculitis and Hydrocephalus in a Patient With Haematological Malignancy: A Case Report and Literature Review.
Cureus
May 2024
Department of Internal Medicine, Monmouth Medical Center, Long Branch, USA.
Meningitis, an infection of the meninges of the central nervous system (CNS), can advance quickly and carries a mortality rate reaching 30% among affected patients. It may become complicated by conditions such as hydrocephalus, ventriculitis, and cerebral abscess. Here, we describe a case of meningitis that was complicated by pyogenic ventriculitis and hydrocephalus in a patient with diffuse large B-cell lymphoma (DLBCL) who underwent chemotherapy and radiotherapy.
View Article and Find Full Text PDFCisternostomy is not beneficial to reduce the occurrence of post-traumatic hydrocephalus in Traumatic Brain Injury.
Acta Neurochir (Wien)
April 2024
Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Background: The Cisternostomy is a novel surgical concept in the treatment of Traumatic Brain Injury (TBI), which can effectively drain the bloody cerebrospinal fluid from the skull base cistern, reduce the intracranial pressure, and improve the return of bone flap, but its preventive role in post-traumatic hydrocephalus (PTH) is unknow. The purpose of this paper is to investigate whether Cisternostomy prevents the occurrence of PTH in patients with moderate and severe TBI.
Methods: A retrospective analysis of clinical data of 86 patients with moderate and severe TBI from May 2019 to October 2021 was carried out in the Brain Trauma Center of Tianjin Huanhu Hospital.
Bacterial Meningitis in Buffaloes in Brazil.
Animals (Basel)
February 2024
Departamento de Epidemiologia e Saúde Pública (DESP), Instituto de Veterinária (IV), Universidade Federal Rural do Rio de Janeiro (UFRRJ), Seropédica 23890-000, Brazil.
Article Synopsis
- - Meningitis is an inflammation of the membranes around the central nervous system, and its manifestation in water buffaloes has been inadequately documented; five cases of the condition were examined in adult Murrah and Mediterranean breed buffaloes from Castanhal, Brazil.
- - Clinical signs included neurological symptoms such as lethargy, difficulty moving, and convulsions; significant findings included loss of horn material, bloody discharge from the frontal sinus, and a notable increase in neutrophils in blood tests.
- - Necropsy revealed severe adherence of the dura mater, presence of purulent exudate on the brain and spinal cord, and cloudy cerebrospinal fluid, confirming a diagnosis of bacterial fibrinopurulent meningitis
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