The existence of an intrinsic electrical platform in the heart, taking over the impulse formation and transmission, is a relatively recent discovery. Leonardo Da Vinci in 1510 wrote that the heart is self-moving. Harvey in 1628 observed that the cardiac movement is seen to begin from the auricles. Purkinje in 1839 discovered at the microscope a network of large, pale muscular cells in the ventricles. His in 1893 showed a muscle bundle connecting the atrial to the ventricular septum. Tawara in 1906 found a node at the atrial origin of His bundle. Finally, Keith and Flack observed a structure of primitive muscular fibres at the sino-atrial junction, where "the dominating rhythm of the heart is believed to normally arise".
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.ijcard.2020.04.076 | DOI Listing |
Biomedicines
December 2024
IRCCS Humanitas Research Hospital, Rozzano, 220089 Milan, Italy.
Cellular senescence has emerged as a fascinating frontier in biological research and now presents profound implications across diverse fields, from aging research to cancer therapy [...
View Article and Find Full Text PDFSci One Health
July 2024
Institute of Applied Microbiology, Xinjiang Academy of Agricultural Sciences, Urumqi 830091, Xinjiang Uygur Autonomous Region, China.
Background: Camels, known as the enduring "ships of the desert," host a complex gut microbiota that plays a crucial role in their survival in extreme environments. However, amidst the fascinating discoveries about the camel gut microbiota, concerns about antibiotic resistance have emerged as a significant global challenge affecting both human and animal populations. Indeed, the continued use of antibiotics in veterinary medicine has led to the widespread emergence of antibiotic-resistant bacteria, which has worsened through gene transfer.
View Article and Find Full Text PDFOphthalmic Plast Reconstr Surg
January 2025
John F. Hardesty, MD, Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, Missouri, U.S.A.
Purpose: To review the long history of wound management, including the methods of skin closure, asepsis, and anesthesia. Periocular techniques will be emphasized.
Methods: Literature searches and cross-referencing were used to identify historic reports addressing the management of wounds.
Chaos
January 2025
School of Mechanical and Power Engineering, Zhengzhou University, Science Road 100, 450001 Zhengzhou, China.
In this paper, the complex and dynamically rich distribution of stable phases in the well-known discrete Ikeda map is studied in detail. The unfolding patterns of these stable phases are described through three complementary stability diagrams: the Lyapunov stability diagram, the isoperiod stability diagram, and the isospike stability diagram. The adding-doubling complexification cascade and fascinating non-quantum chiral pairs are discovered, marking the first report of such structures in discrete mapping.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Electrical and Electronic Engineering, Bangladesh University of Engineering and Technology, Dhaka, 1205, Bangladesh.
Prediction and discovery of new materials with desired properties are at the forefront of quantum science and technology research. A major bottleneck in this field is the computational resources and time complexity related to finding new materials from ab initio calculations. In this work, an effective and robust deep learning-based model is proposed by incorporating persistent homology with graph neural network which offers an accuracy of and an F1 score of in classifying topological versus non-topological materials, outperforming the other state-of-the-art classifier models.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!