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http://dx.doi.org/10.1007/s10646-020-02214-3 | DOI Listing |
Sci Rep
November 2024
Division of Biochemistry, Department of Physiology and Biochemistry, University of Veterinary Medicine Budapest, István Street 2, Budapest, 1078, Hungary.
Neotrop Entomol
October 2024
Plant Protection Research Institute, Agricultural Research Center, Sides Agriculture Research Station, Al-Giza, Egypt.
Int J Radiat Oncol Biol Phys
November 2024
Department of Radiation Oncology, Fujian Medical University Union Hospital, Fuzhou, People's Republic of China; Fujian Key Laboratory of Intelligent Imaging and Precision Radiotherapy for Tumors, Fujian Medical University, Fuzhou, People's Republic of China; Clinical Research Center for Radiology and Radiotherapy of Fujian Province (Digestive, Hematological and Breast Malignancies), Fuzhou, People's Republic of China. Electronic address:
Purpose: With the coming era of digital medicine and healthcare technology, mathematical modeling of tumors has become a key step to optimize and realize precision radiation therapy. The purpose of this study was to develop a mathematical model for simulating the change of head and neck (HN) tumor volume during radiation therapy.
Methods And Materials: A formula was developed to describe the dynamic change of oxygenated compartment within a tumor, which was combined with the lethal lesions model to describe various cell processes during radiation therapy, including potentially lethal lesion repair and misrepair, cell proliferation/loss, and tumor reoxygenation.
Sci Total Environ
June 2024
Division of Biotechnology, SELS Center, College of Environmental and Bioresource Sciences, Jeonbuk National University, Iksan, Jeonbuk 54596, South Korea. Electronic address:
Despite the theoretical risk of forming halogenated methylparabens (halo-MePs) during water chlorination in the absence or presence of bromide ions, there remains a lack of in vivo toxicological assessments on vertebrate organisms for halo-MePs. This research addresses these gaps by investigating the lethal (assessed by embryo coagulation) or sub-lethal (assessed by hatching success/heartbeat rate) toxicity and teratogenicity (assessed by deformity rate) of MeP and its mono- and di-halogen derivatives (Cl or Br) using Japanese medaka embryos. In assessing selected apical endpoints to discern patterns in physiological or biochemical alterations, heightened toxic impacts were observed for halo-MePs compared to MeP.
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