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Unprotected distal left main percutaneous intervention.

Prog Cardiovasc Dis

December 2024

Division of Cardiovascular Medicine, Department of Medicine, University of Virginia, Charlottesville, VA 22908, United States of America. Electronic address:

Revascularization has been demonstrated to be clearly superior to medical therapy for significant unprotected left main coronary artery (LMCA) disease. Coronary artery bypass graft surgery (CABG) has a class 1 indication in both the American and European society guidelines for the treatment of LMCA disease. However, for the population of patients who are declined CABG after a heart team evaluation, percutaneous coronary interventional (PCI) may be an efficacious alternative.

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Background: Elective unprotected left main (ULM) percutaneous coronary intervention (PCI) has long-term mortality rates comparable to surgical revascularization, thanks to advances in drug-eluting stent (DES) design, improved PCI techniques, and frequent use of intravascular imaging. However, urgent PCI of ULM culprit lesions remains associated with high in-hospital mortality and unfavourable long-term outcomes, including DES restenosis and stent thrombosis (ST). This analysis aimed to examine the long-term outcomes and healing of DES implanted in ULM during primary PCI using high-resolution optical coherence tomography (OCT) imaging.

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Background: The Magenta Elevate is a 9-F, self-expanding, catheter-mounted pump delivered sheathed through a commercially available 10-F femoral introducer over the wire to the left ventricle (LV), providing temporary hemodynamic support up to an equivalent of normal cardiac output.

Objectives: The authors sought to assess the feasibility and outcomes of Elevate-supported high-risk percutaneous coronary intervention (HR-PCI) in a first-in-human study and study the hemodynamic impact of high-output support during prolonged interventional left main coronary artery (LM) occlusions.

Methods: In this study, 14 patients underwent Elevate-supported HR-PCI, with 8 patients undergoing 20 prolonged (39 ± 16 seconds) balloon occlusions of an unprotected LM.

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Conflict resolution behavior of autonomous vehicles at intersections under mixed traffic environment.

Accid Anal Prev

December 2024

Department of Civil and Environmental Engineering, Michigan State University, Lansing, MI 48910, USA. Electronic address:

Navigating intersections is a major challenge for autonomous vehicles (AVs) because of the complex interactions between different roadway user types, conflicting movements, and diverse operational and geometric features. This study investigated intersection-related AV-involved traffic conflicts by analyzing the Arogoverse-2 motion forecasting dataset to understand the driving behavior of AVs at intersections. The conflict scenarios were categorized into AV-involved and no AV conflict scenarios.

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