Angiotensin-converting enzyme inhibitors from Vahl.

Phytochemical research of the acetate and methanol extracts of the aerial parts (flowers, leaves and stems) of allowed to obtain seventeen known compounds (): three of them (), had already been described for this species, while the others () are described for the first time for S. elegans. All isolated compounds were characterized using spectroscopic techniques and mass spectrometry and were evaluated in the Angiotensin I-converting enzyme (ACE) inhibition model, where the phenolic compounds (, and ) had the same inhibitory effect as lisinopril at 0.02 mg/mL. The terpenes showed a moderate inhibitory capacity at a concentration of 0.2 mg/mL.