Scaling-up of Haematococcus pluvialis production in stirred tank photobioreactor.

Bioresour Technol

Manisa Celal Bayar University, Faculty of Engineering, Department of Bioengineering, 45119 Manisa, Turkey. Electronic address:

Published: August 2020

AI Article Synopsis

  • The study aimed to evaluate different scale-up criteria for producing Haematococcus pluvialis in larger stirred tank photobioreactors (PBRs).
  • Constant volumetric power input (P/V) proved to be the most effective scale-up strategy, leading to higher yields of carotenoids.
  • The findings suggest that using this criterion can enhance carotenoid production and antioxidant activity, showing potential for commercial applications.

Article Abstract

The objective of this study was to evaluate three most common scale-up criteria for Haematococcus pluvialis production from cultivation bottles to 2 and 10 L of stirred tank PBRs. Constant volumetric power input (P/V) was found to be the most suitable criterion for H. pluvialis production. Total carotenoid amount per biomass concentration in 2 L and 10 L stirred tank PBRs were determined to be 4.57 mg/g and 4.77 mg/g, respectively. Antioxidant activity of total carotenoids extracted from H. pluvialis was also higher at constant P/V criterion where 46.91% inhibition rate with a total phenolic content of 11.76 mg gallic acid/L was achieved. Obtained results could be used to expand the bioproduction of H. pluvialis and its extracts in commercial scale.

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http://dx.doi.org/10.1016/j.biortech.2020.123434DOI Listing

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