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PD-L1 as a Biomarker in Gastric Cancer Immunotherapy.
J Gastric Cancer
January 2025
Department of Pathology and Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Combining chemotherapy with immune checkpoint inhibitors (ICIs) that target the programmed death-1 (PD-1) protein has been shown to be a clinically effective first-line treatment for human epidermal growth factor receptor 2 (HER2)-negative and -positive advanced or metastatic gastric cancer (GC). Currently, PD-1 inhibitors combined with chemotherapy are the standard treatment for patients with HER2-negative/positive locally advanced or metastatic GC. Programmed death-ligand 1 (PD-L1) expression, as assessed using immunohistochemistry (IHC), is a crucial biomarker for predicting response to anti-PD-1/PD-L1 agents in various solid tumors, including GC.
View Article and Find Full Text PDFPopulational Uses of Complementary Therapies via a Digital Platform in France: Motivations and Needs.
J Integr Complement Med
January 2025
Integrative Medecine, Rafael Institute, Levallois-Perret, France.
Complementary and integrative medicine (CIM) encompasses over 400 modalities, according to the World Health Organization (WHO). In 2011, 70% of the European Union's population reported having used CIM at least once, with 25% using it annually. This study examines the engagement, motivations, and satisfaction of users in the French health care system through data from Medoucine, France's largest online platform for complementary therapies.
View Article and Find Full Text PDFReasons, associated factors, and attitudes toward breastfeeding mothers' use of complementary medicine products: a study from Türkiye.
Int Breastfeed J
January 2025
Instutite of Health Sciences, Istanbul Medipol University, Istanbul, Turkey.
Background: The use of Complementary Medicine Products (CMPs) has been increasing worldwide, including among breastfeeding mothers. This study aims to investigate the reasons and associated factors of CMP use among breastfeeding mothers in Turkey, alongside their attitudes and experiences.
Methods: A descriptive cross-sectional study was conducted using a self-administered, anonymous online survey between 17 December 2023 and 17 March 2024.
Background And Objectives: Polycystic ovary syndrome (PCOS) is a prevalent female reproductive and metabolic disorder. Among patients with chronic conditions, an increasing number have approached complementary and alternative medicine (CAM) to cope with their disease. This study aimed to assess the use of CAM among females with PCOS in Jordan.
View Article and Find Full Text PDFMedical Students' Knowledge and Perceptions of Herbal Medicine in Saudi Arabia: Should Medical Schools Take Immediate Action?
Adv Med Educ Pract
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Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al Qura University, Makkah, Saudi Arabia.
Background: Herbal medicine is integral to Saudi Arabia's Vision 2030, which seeks to improve the healthcare system and promote alternative practices while ensuring safety through education and research. This study aims to evaluate medical students' knowledge and perceptions regarding herbal medicine in Saudi Arabia.
Methods: A cross-sectional study was conducted among medical students in three medical colleges in Saudi Arabia over a six-month period from 1 February to 31 July 2024.
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