AI Article Synopsis
- - The study examined how different types of primary lung cancers enhance on a 2-phase dynamic CT scan, involving 217 patients with various lung cancer types, primarily adenocarcinomas and squamous cell carcinomas.
- - After excluding small cell lung carcinomas, the research showed that squamous cell carcinomas had significantly higher attenuation values in late-phase scans compared to adenocarcinomas.
- - The findings suggest that dynamic lung CT can help differentiate between non-small cell lung carcinoma types, with specific Hounsfield unit thresholds providing varying levels of accuracy for classification.
Article Abstract
The aim of this study was to explore enhancement patterns of different types of primary lung cancers on 2-phase dynamic computed tomography (CT). This study included 217 primary lung cancer patients (141 adenocarcinomas [ADs], 48 squamous cell carcinomas [SCCs], 20 small cell lung carcinomas [SCLCs], and 8 others) who were examined using a 2-phase dynamic scan. Regions of interest were identified and mean enhancement values were calculated. After excluding the 20 SCLCs because these lesions had different clinical stages from the other cancer types, the mean attenuation values and subtractions between phases were compared between types of non-small cell lung carcinomas (NSCLCs) using the Kruskal-Wallis test. Late phase attenuation and attenuation of the late minus unenhanced phase (LMU) of SCCs were significantly higher than those of ADs (p<0.05). To differentiate SCC and AD in the late phase, a threshold of 80.21 Hounsfield units (HU) gave 52.9% accuracy. In LMU, a threshold of 52.16 HU gave 59.3% accuracy. Dynamic lung CT has the potential to aid in differentiating among NSCLC types.
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| http://dx.doi.org/10.18926/AMO/58271 | DOI Listing |
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