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Tudor-domain containing protein 5-like promotes male sexual identity in the Drosophila germline and is repressed in females by Sex lethal.
PLoS Genet
July 2019
Department of Biology, Johns Hopkins University, Baltimore, Maryland, United States of America.
Article Synopsis
- The production of male or female gametes in sexually reproducing organisms is determined by the correct sexual identity in the germline, with the gene Sex lethal (Sxl) playing a crucial role in D. melanogaster.
- Research reveals that the loss of Sxl does not result in overall masculinization in the germline, but instead impacts specific genes critical for male germline identity, notably Phf7.
- Additionally, the study identifies Tdrd5l as an important Sxl-regulated gene that promotes male fertility and differentiation, and its expression is linked to post-transcriptional gene regulation in male germ cells.
Genome-wide association study for semen volume and total number of sperm in Holstein-Friesian bulls.
Anim Reprod Sci
December 2014
University of Warmia and Mazury in Olsztyn, Department of Animal Genetics, 10-719 Olsztyn, Poland. Electronic address:
In artificial insemination industry bulls producing high volume of semen with relatively high concentration of sperm are very desirable since they ensure stable production of commercial straws especially in case of top bulls. The aim of the study was to screen the entire bull genome to identify markers and candidate genes underlying semen volume (SV) and total number of sperm (TNS) in ejaculate produced by Holstein-Friesian bulls. Data on semen production were retrieved from records of AI center and included a population of 877 Holstein-Friesian bulls.
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