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The effects of delta-9-tetrahydrocannabinol (THC) on inflammation: A review. | LitMetric

The effects of delta-9-tetrahydrocannabinol (THC) on inflammation: A review.

Cell Immunol

Division of Surgical Research, Cooper University Hospital, Camden, NJ, USA. Electronic address:

Published: April 2020

AI Article Synopsis

  • * CBD, another key component of marijuana, also exhibits similar anti-inflammatory properties.
  • * The review explores how THC's effects on inflammation could be significant for wound healing, particularly in the context of surgical applications.

Article Abstract

THC is the main psychoactive compound found in marijuana. A number of studies over the past few decades, both in vitro and in vivo, have demonstrated that THC down-regulates the inflammatory process through various mechanisms. Similar findings have been demonstrated with CBD, the other major bioactive component of marijuana. Given the essential role that inflammation plays in early wound healing, it is possible that marijuana, or its individual constituents, may impact this process. Herein, we review the existing literature related to the effects of THC on inflammation and potentially wound healing, and discuss how this connection may be relevant from a surgical perspective.

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Source
http://dx.doi.org/10.1016/j.cellimm.2020.104111DOI Listing

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