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[Annual research progress in chronic obstructive pulmonary disease 2024].
Zhonghua Jie He He Hu Xi Za Zhi
January 2025
National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Hetao Institute of Guangzhou National Laboratory, Shenzhen518000, China.
Article Synopsis
- COPD is a growing global health issue, with recent advancements in early detection and personalized treatment, highlighting the importance of monitoring early-stage disease for better prognosis.
- Research has identified critical areas in the lungs as initial sites of damage, and specific biomarkers may help track different disease progression patterns.
- New treatment strategies, including triple inhalation therapy and innovative medications, show promise in managing symptoms and improving patient outcomes in COPD, with ongoing research aimed at understanding disease variability.
Aortic Pulse Wave Velocity Determined with Oscillometric Pulse Wave Analysis Algorithm Antares Is an Independent Predictor of Major Adverse Cardiovascular Events: A Prospective Cohort Study.
J Clin Med
November 2024
Praxis Dres. Gille/Baulmann, 53359 Rheinbach, Germany.
: Aortic pulse wave velocity (aPWV) is a well-established surrogate marker of arterial stiffness. The Antares algorithm offers a method for determining aPWV from oscillometric blood pressure waveforms without requiring additional inputs. This prospective study aimed to evaluate the association and prognostic value of aPWV, determined by Antares, in predicting major adverse cardiovascular events (MACE).
View Article and Find Full Text PDFAsthma is a highly prevalent but heterogenous condition. Uncontrolled disease is relatively common and may be due to ongoing inflammation and/or persisting bronchial hyper-reactivity. Bronchial thermoplasty has been in use for many years but optimal case selection and post-procedure assessment remain uncertain.
View Article and Find Full Text PDFSmall airway involvement in severe asthma: how common is it and what are its implications?
Monaldi Arch Chest Dis
December 2024
Asthma is a prevalent chronic respiratory disease affecting all age groups globally, causing significant morbidity and mortality. Small airway involvement, often undetected by traditional spirometry, has emerged as a critical aspect of asthma pathophysiology, especially in severe cases. This retrospective observational study aimed to assess small airway dysfunction using impulse oscillometry (IOS) in 94 severe asthma patients.
View Article and Find Full Text PDFOscillometry-defined small airways dysfunction as a treatable trait in asthma.
Ann Allergy Asthma Immunol
November 2024
University of Dundee School of Medicine, Dundee, United Kingdom. Electronic address:
Article Synopsis
- * The oscillometry technique helps measure airflow resistance and reactance during normal breathing, providing insights into airway function.
- * A new management approach focuses on "treatable traits" to customize asthma treatment by identifying and addressing factors that affect control, including small airways dysfunction and the effectiveness of specific medications.
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