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P120catenin tuning of VE-cadherin endocytosis controls collective cell behavior during angiogenesis. | LitMetric

P120catenin tuning of VE-cadherin endocytosis controls collective cell behavior during angiogenesis.

J Cell Biol

Cell Polarity, Migration and Cancer Unit, Institut Pasteur, UMR3691 Centre National de la Recherche Scientifique, Equipe Labellisée Ligue Contre le Cancer, Paris, France.

Published: May 2020

How cells can stick together while moving through a complex environment is not fully understood. In this issue, Grimsley-Myers et al. (2020. J. Cell Biol.https://doi.org/10.1083/jcb.201909081) demonstrate that, in the case of blood vessel formation, the balance between the maintenance of endothelial integrity and the dynamics of cell-cell contacts required for collective migration relies on VE-cadherin endocytosis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199857PMC
http://dx.doi.org/10.1083/jcb.202003005DOI Listing

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