In recent years, men who have sex with men (MSM) constitute a major group of HIV transmission in China. High primary drug-resistance (PDR) rate in MSM also represents a serious challenge for the Chinese antiretroviral therapy (ART) program. To assess the efficiency of ART in controlling HIV/AIDS infection among MSM, we developed a compartmental model for the annually reported HIV/AIDS MSM from 2007 to 2019 in the Zhejiang Province of China. R0 was 2.3946 (95% CI (2.2961-2.4881)). We predict that 90% of diagnosed HIV/AIDS individuals will have received treatment till 2020, while the proportion of the diagnosed remains as low as 40%. Even when the proportion of the diagnosed reaches 90%, R0 is still larger than the level of AIDS epidemic elimination. ART can effectively control the spread of HIV, even in the presence of drug resistance. The 90-90-90 strategy alone may not eliminate the HIV epidemic in Chinese MSM. Behavioural and biologic interventions are the most effective interventions to control the HIV/AIDS epidemic among MSM.
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http://dx.doi.org/10.1017/S0950268820000850 | DOI Listing |
PLoS One
January 2025
Cardiometabolic, Exercise, and Lifestyle Laboratory, University of New Brunswick, Fredericton, NB, Canada.
Blood flow restriction training (BFRT) has been previously studied as an alternative form of resistance training to gain lean mass and improve performance outcomes. However, in all exercise studies of BFRT, the proportion of female participants represents only 17-29% of all research participants. This highlights a strong underrepresentation of females and the need for more knowledge on the impact of BFRT and sex differences.
View Article and Find Full Text PDFJ Head Trauma Rehabil
January 2025
Author Affiliations: Program Executive Office, Defense Healthcare Management Systems, Arlington, Virginia (Ms Wal and Dr Caban); National Center for Collaborative Healthcare Innovation (NCCHI), VA Palo Alto Health Care System, Palo Alto, California (Mr Hoover); Department of Health Law, Policy and Management, Boston University School of Public Health, Boston, Massachusetts (Dr Adams); Veterans Health Administration Rocky Mountain Mental Illness Research Education and Clinical Center, Aurora, Colorado (Drs Adams and Forster); Department of Physical Medicine & Rehabilitation, University of Colorado, Anschutz Medical Campus, Aurora, Colorado (Dr Forster); and Uniformed Services University of the Health Sciences, Graduate School of Nursing, Bethesda, Maryland (Dr Engler).
Objective: To investigate the incidence of early/unplanned (E/U) separations following mild traumatic brain injury (mTBI) and assess whether sex impacts the hazard of separation.
Setting: Military Health System (MHS).
Participants: Active duty service members (N = 75,730) with an initial mTBI diagnosis in military records between January 2011 and January 2018.
Eur J Prev Cardiol
January 2025
Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Aim: Sleep apnoea syndrome (SAS) is a common sleep disorder associated with heightened cardiovascular risks, yet sex-specific differences in these risks remain unclear.
Methods: This retrospective observational cohort study utilized the JMDC Claims Database, covering >5 million individuals in Japan. We analyzed data from 4,173,702 individuals (2,406,930 men, 1,766,772 women) after excluding those with central SAS, cardiovascular disease, and incomplete lifestyle questionnaire data.
Drugs Aging
January 2025
Department of Preventive Medicine and Education, Medical University of Gdansk, Gdańsk, Poland.
Introduction: Older adults represent a growing proportion of the general population. Nonsteroidal anti-inflammatory drugs (NSAIDs) constitute a group of medicines that are both necessary, owing to their anti-inflammatory, analgesic, and cardioprotective abilities, and potentially harmful, owing to their side effects.
Objectives: This study provides a comprehensive analysis of NSAID usage patterns among Polish adults aged 60 years and older.
Qual Life Res
January 2025
Eye and Vision Research, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Purpose: To assess the relationship between quality of life (QoL) and ocular surface health within a Finnish population-based cohort.
Methods: A cross-sectional study involved 601 individuals born between the years 1933-1956. Ocular surface health and dry eye disease (DED) were clinically evaluated using several diagnostic tests.
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