Introduction: Kawasaki disease is an acute vasculitis of unknown etiology. The epidemiological data available for Nepal remains insufficient. In Nepal, Kawasaki disease has only been reported in cases of brief reports, leaving the true disease burden unknown. Many cases go undiagnosed and untreated due to a lack of knowledge regarding this entity. The objective of this study was to find the prevalence of Kawasaki disease in a tertiary care hospital.
Methods: This descriptive cross-sectional study was carried out in a tertiary care hospital of Nepal from 2013 to 2018 after taking ethical approval from the Institutional Review Committee. The sample size was calculated and the consecutive sampling method was done. Data collection and entry was done in Microsoft Excel, point estimate at 99% Confidence Interval was calculated along with frequency and proportion for binary data.
Results: The overall prevalence of Kawasaki disease was found to be 0.10% at 95% Confidence Interval (0.07-0.13%) among 11,416 patients under the age of 5 years admitted in pediatrics ward. There were 4 (33.33%) cases of complete Kawasaki and 8 (66.67%) cases of incomplete Kawasaki. There were 9 (75%) males and 3 (25%) females and the male to female ratio was 3:1. There was a male preponderance. The age at diagnosis ranged between 4 and 60 months. The median age at diagnosis was 10.5 months. The most common presentation was fever, conjunctivitis, rash, and oral changes.
Conclusions: Prevalence of Kawasaki disease was found to be lesser compared to other studies done in other countries. Knowledge of Kawasaki disease among Nepalese pediatricians should be enhanced to guarantee the appropriate diagnosis and treatment of this disease.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580414 | PMC |
| http://dx.doi.org/10.31729/jnma.4746 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Several studies explored the associations of pre-albumin (PA)/albumin (ALB) and ALB-combined indicators (prognostic nutrition index [PNI], albumin-to-globulin ratio [AGR], bilirubin-to-albumin [BAR], and C-reactive protein/albumin ratio [CAR]) with intravenous immunoglobulin (IVIG) resistance and coronary artery lesions (CALs) in Kawasaki disease (KD) patients. However, the results were controversial. A meta-analysis was conducted to reconfirm their associations and predictive performance.
View Article and Find Full Text PDFAsian Pacific Society of Cardiology Position Statement on the Use of Transcatheter Aortic Valve Implantation in the Management of Aortic Stenosis.
JACC Asia
December 2024
Department of Cardiology, National Heart Centre Singapore, Singapore.
Transcatheter aortic valve implantation (TAVI) has been established as an effective treatment modality in patients with severe aortic stenosis (AS) and the uptake of TAVI is rapidly growing in the Asia-Pacific region. However, there exist a heterogeneity in the management of aortic stenosis and the use of TAVI among countries in the region. Reasons for these differences include anatomic variations, disparity in healthcare resources and infrastructure, and the lack of consensus on the optimal management of AS in the Asia-Pacific region.
View Article and Find Full Text PDFAgreement between methods to assess potassium intake in patients with chronic kidney disease.
Clin Nutr ESPEN
January 2025
Post Graduation Program in Medical Science, Rio de Janeiro State University, Rio de Janeiro, 20550-900, Brazil; Department of Applied Nutrition, Nutrition Institute, Rio de Janeiro State University, Rio de Janeiro, 20550-900, Brazil. Electronic address:
Background & Aims: In the general population, 24-hour urine potassium excretion is considered the reference standard for estimating potassium intake. However, its agreement with food records and spot urine collections in adults living with chronic kidney disease (CKD) is not well-established. Given the risk of hyperkalemia related to changes in renal potassium handling, understanding if this reference standard is appropriate for the CKD population is important.
View Article and Find Full Text PDFDevelopment and validation of a nomogram-based prognostic model to predict coronary artery lesions in Kawasaki disease from 6847 children in China.
Comput Methods Programs Biomed
January 2025
Department of Cardiology, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430016, China. Electronic address:
Background And Objective: Predicting potential risk factors for the occurrence of coronary artery lesions (CAL) in children with Kawasaki disease (KD) is critical for subsequent treatment. The aim of our study was to establish and validate a nomograph-based model for identifying children with KD at risk for CAL.
Methods: Hospitalized children with KD attending Wuhan Children's Hospital from Jan 2011 to Dec 2023 were included in the study and were grouped into a training set (4793 cases) and a validation set (2054 cases) using a simple random sampling method in a 7:3 ratio.
Clinical practice guidelines for management of disseminated intravascular coagulation in Japan 2024. Part 3: solid cancers and vascular abnormalities.
Int J Hematol
January 2025
Associated Department With Mie Graduate School of Medicine, Mie Prefectural General Medical Center, Yokkaichi, Japan.
This study discusses disseminated intravascular coagulation (DIC) associated with solid cancers and various vascular abnormalities, both of which generally exhibit chronic DIC patterns. Solid cancers are among the most significant underlying diseases that induce DIC. However, the severity, bleeding tendency, and progression of DIC vary considerably depending on the type and stage of the cancer, making generalization difficult.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!