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| http://dx.doi.org/10.1016/j.thromres.2020.04.021 | DOI Listing |
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Clinical characteristics and BGA-optimized pretest probability of pulmonary embolism in the elderly.
Med Klin Intensivmed Notfmed
January 2025
University Heart Center Lübeck, Department of Cardiology, Angiology and Intensive Care Medicine, University of Lübeck, German Center for Cardiovascular Research (DZHK), partner site Hamburg/Kiel/Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.
Background: Pulmonary arterial embolism (PE) is not well characterized in elderly patients. In addition, unnecessary computed tomography pulmonary angiography (CTPA) examinations are often performed within this patient group, especially if the pretest probability is low.
Objective: To identify differences in clinical presentation in patients aged ≥80 years compared to patients <80 years and the effect of a BGA-optimized pretest probability to reduce unnecessary CTPAs according to age category.
Combination of age-adjusted d-dimer, platelet distribution width and other factors predict preoperative deep venous thrombosis in elderly patients with femoral neck fracture.
BMC Surg
December 2024
Department of Vascular Surgery, the Third Hospital of Hebei Medical University, Shijiazhuang, 050051, Hebei, P.R. China.
Purpose: This retrospective cohort study aimed to identify factors associated with preoperative deep venous thrombosis (DVT) in elderly patients with femoral neck fractures, and to investigate whether combining these factors could improve the ability to predict DVT.
Method: Medical records and laboratory test results were reviewed patients presenting with a femoral neck fracture and receiving routine chemoprophylaxis for DVT between January 2020 and December 2023 in a tertiary referral, university-affiliated hospital. Preoperative DVT was confirmed by Doppler ultrasound or CT venography.
A Comparative Analysis of the Impact of Severe Acute Respiratory Syndrome Coronavirus 2 Infection on the Performance of Clinical Decision-Making Algorithms for Pulmonary Embolism.
J Clin Med
November 2024
Department of Emergency Medicine, Fatih Sultan Mehmet Education and Research Hospital, University of Health Sciences, Istanbul 34752, Turkey.
: This study aimed to compare the diagnostic accuracy of the Wells and Geneva scores using a 500 ng/mL D-dimer cutoff, as well as the age-adjusted D-dimer (AADD), YEARS, and pulmonary embolism graduated D-dimer (PEGeD) algorithms, in patients with and without COVID-19. Various D-dimer cutoffs were also evaluated. This retrospective study included emergency department patients who underwent computed tomography pulmonary angiography (CTPA) for suspected pulmonary embolism (PE).
View Article and Find Full Text PDFFailure rate of D-dimer testing in patients with high clinical probability of pulmonary embolism: Ancillary analysis of three European studies.
Acad Emerg Med
November 2024
Emergency Department, Pitié Salpêtrière Hospital, Paris, France.
Background: In patients with a high clinical probability of pulmonary embolism (PE), the high prevalence can lower the D-dimer negative predictive value and increase the risk of diagnostic failure. It is therefore recommended that these high-risk patients should undergo chest imaging without D-dimer testing although no evidence supports this recommendation.
Objective: The objective was to evaluate the safety of ruling out PE based on D-dimer testing among patients with a high clinical probability of PE.
Diagnosis of pulmonary embolism in patients with haemoptysis: the POPEIHE study.
ERJ Open Res
September 2024
Department of Emergency Medicine, Careggi Hospital, Azienda Ospedaliero Universitaria Careggi, Florence, Italy.
Aim: To determine the prevalence and characteristics of pulmonary embolism (PE) in patients presenting with haemoptysis. Additionally, we assessed the efficiency and failure rates of different clinical diagnostic algorithms for PE in this patient population.
Methods: We enrolled consecutive adult patients who presented to nine Italian emergency departments with haemoptysis as the primary complaint.
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