We describe a novel endovascular technique in which three 0.014″ guidewires are placed in parallel through a 0.035″ lumen catheter, in order to create a stiff platform to allow for delivery of 0.035″ profile devices through challenging anatomy. Three illustrative cases are presented: a difficult aortic bifurcation during lower extremity intervention, a tortuous internal iliac artery during placement of an iliac branch device, and salvage of a renal artery after inadvertent coverage during proximal cuff deployment for type 1a endoleak. We also quantify the relative stiffness of the triple 0.014″ wire configuration, using several well-known 0.035″ wires for comparison. The "triple wire technique" is an effective method for tracking endovascular devices through difficult tortuous anatomy, and can be used in a variety of clinical settings. The technique is especially useful when a traditional, stiff 0.035″ wire will not track without "kicking out." Each 0.014″ wire is reasonably soft and traverses the tortuous vessel easily, but when the 3 wires are used together as a rail it provides a stiff enough platform for delivery.
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http://dx.doi.org/10.1016/j.avsg.2020.04.021 | DOI Listing |
Front Robot AI
December 2024
CREATE-Lab, Department of Mechanical Engineering, Swiss Federal Technology Institute of Lausanne (EPFL), Lausanne, Switzerland.
Creativity and style in music playing originates from constraints and imperfect interactions between instruments and players. Digital and robotic systems have so far been unable to capture this naturalistic playing. Whether as an additional tool for musicians, function restoration with prosthetics, or artificial intelligence-powered systems, the physical embodiment and interactions generated are critical for expression and connection with an audience.
View Article and Find Full Text PDFCurr Protoc
December 2024
Research Unit of Health Sciences and Technology, Faculty of Medicine, University of Oulu, Oulu, Finland.
Osteoarthritis (OA) is one of the most prevalent joint diseases globally, characterized by the progressive breakdown of articular cartilage, resulting in chronic pain, stiffness, and loss of joint function. Despite its significant socioeconomic impact, therapeutic options remain limited, largely due to an incomplete understanding of the molecular mechanisms driving cartilage degradation and OA pathogenesis. Recent advances in in vitro modeling have revolutionized joint tissue research, transitioning from simplistic two-dimensional cell cultures to sophisticated three-dimensional (3D) constructs that more accurately mimic the physiological microenvironment of native cartilage.
View Article and Find Full Text PDFSensors (Basel)
November 2024
National Key Laboratory of Automotive Chassis Integration and Bionics, Changchun 130022, China.
The accuracy of the control model is essential for the effectiveness of model-based control methods. However, factors such as model simplification, parameter variations, and environmental noise can introduce inaccuracies in vehicle state descriptions, thereby compromising the precision of path tracking. This study introduces data-driven enhancements for an MPC-based path tracking controller in autonomous vehicles (DD-PTC).
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Department of Experimental Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy.
Breast cancer is the most common cancer and the second leading cause of cancer-related death in women. In advanced stages of the disease, breast cancer can spread and metastasize to the bone, contributing to malignant progression. The roles of tissue stiffness and remodeling of the tumor microenvironment are relevant in influencing cancer progression and invasiveness, but they are still poorly understood.
View Article and Find Full Text PDFJ Exp Biol
December 2024
School of Life & Environmental Sciences, University of Lincoln, Joseph Banks Laboratories, Green Lane, Lincoln LN6 7DL, UK.
Animals often leap from substrates that give way under them, such as leaves, soft ground or flexible branches. This provides an added complexity for latch-mediated spring-actuated (LaMSA) jumping animals because the spring-loaded system often works so quickly that neural feedback cannot adjust for errors caused by a yielding substrate. We studied a LaMSA jumper, the grasshopper, to determine how the mechanical properties of a substrate giving way under them would affect the kinematics of the jump.
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