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Vitamin B, B, and B Intakes and Risk of Gastric Cancer: Findings from a Case-Control Study.
Nutrients
December 2024
University of Pittsburgh Medical Center, Hillman Cancer Center, Pittsburgh, PA 15261, USA.
Background/objectives: Gastric cancer is one of the leading malignancies worldwide. B vitamins play important roles in DNA synthesis and methylation because they are considered co-enzymes in one-carbon metabolism. There is inconclusive evidence regarding the associations between dietary vitamins B, B, and B with the risk of gastric cancer in different epidemiologic studies.
View Article and Find Full Text PDFA molecular toxicological study to explore potential health risks associated with ultrafine particle exposure in cold and humid indoor environments.
Ecotoxicol Environ Saf
January 2025
Joint International Research Laboratory of Green Buildings and Built Environments (Ministry of Education), Chongqing University, Chongqing 400045, China; School of the Built Environment, University of Reading, Reading RG6 6DB, UK. Electronic address:
Environmental pollutants including ultrafine particulate matter (UFPs) and adverse meteorological conditions pose significant public health impacts, particularly affecting respiratory health. This study aims to elucidate the synergistic effects of cold-humid conditions and UFPs exposure on respiratory health, utilizing Carbon Black Nanoparticles (CB-NPs) as surrogates for UFPs. Through comprehensive lung function tests, histopathological examinations, and biomarker analyses, this research focuses on the modulation of oxidative stress signaling pathways and NF-κB activation.
View Article and Find Full Text PDFFluorescent "on-off-on" sensor based on N, P co-doped carbon nanoparticles for specific detection of Fe and ascorbic acid.
J Food Drug Anal
December 2024
Zhenjiang College, Zhenjiang, 212000, PR China.
Ascorbic acid (AA) is used as a food additive for its antibacterial and antioxidant properties. However, excessive intake of AA is harmful to humans. Therefore, the detection of Fe and AA is generally recognized to be meaningful.
View Article and Find Full Text PDFTreating myocardial infarction via a nano-ultrasonic contrast agent-mediated high-efficiency drug delivery system targeting macrophages.
Sci Adv
January 2025
Department of Cardiac Surgery, Peking University Third Hospital, Beijing 100191, China.
Following myocardial infarction (MI), the accumulation of CD86-positive macrophages in the ischemic injury zone leads to secondary myocardial damage. Precise pharmacological intervention targeting this process remains challenging. This study engineered a nanotherapeutic delivery system with CD86-positive macrophage-specific targeting and ultrasound-responsive release capabilities.
View Article and Find Full Text PDFFrom Micro to Macro: Understanding the Far-Reaching Consequences of B12 Deficiency on Women's Health.
Public Health Nurs
January 2025
Symbiosis College of Nursing, Symbiosis International (Deemed University), Pune, India.
Background: Vitamin B12 (B12), playing the role of a coenzyme in one-carbon metabolism, is an important vitamin necessary for human health.
Objectives: To systematically review evidence to identify the complications of B12 deficiency among women.
Methods: We conducted a systematic search of quantitative studies on disorders associated with B12 deficiency among women, published in English in the last 25 years (1999-2024), using electronic databases such as Scopus, Web of science, CINAHL, PubMed, and Medline.
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