(L.) Dumort (Asteraceae) -hexane extract displayed high cell proliferation inhibitory activity against acute myeloid leukaemia cells (OCI-AML3) and was therefore subjected to a bioassay-guided multistep separation procedure. Two thymol derivatives, namely 10-acetoxy-8,9-epoxythymol tiglate () and 10-acetoxy-9-chloro-8,9-dehydrothymol (), were isolated and identified by means of NMR spectroscopy. Both of them exhibited a significant dose-dependent inhibition of cell proliferation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221903 | PMC |
| http://dx.doi.org/10.3390/molecules25081893 | DOI Listing |
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