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Development and Validation of an AI-Based Multimodal Model for Pathological Staging of Gastric Cancer Using CT and Endoscopic Images.
Acad Radiol
January 2025
Guangxi Medical University, Nanning, Guangxi 530021, China (C.Z., D.H., B.W., S.W., Y.S., X.W.); Guangxi Key Laboratory of Enhanced Recovery After Surgery for Gastrointestinal Cancer, Nanning, Guangxi 530021, China (C.Z., D.H., B.W., S.W., Y.S., X.W.); Department of Gastrointestinal Gland Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China (D.H., X.W.). Electronic address:
Rationale And Objectives: Accurate preoperative pathological staging of gastric cancer is crucial for optimal treatment selection and improved patient outcomes. Traditional imaging methods such as CT and endoscopy have limitations in staging accuracy.
Methods: This retrospective study included 691 gastric cancer patients treated from March 2017 to March 2024.
Preretinal abnormal tissue before and after pars plana vitrectomy in macula-on rhegmatogenous retinal detachment: a multimodal imaging study.
Br J Ophthalmol
January 2025
Department of Neurosciences, Imaging and Clinical Sciences, University "G. d'Annunzio" Chieti-Pescara, Chieti, Italy.
Purpose: To quantitatively explore preretinal abnormal tissue (PAT) in macula-on rhegmatogenous retinal detachment (RRD) before and after surgery.
Methods: In this case-series study, PAT was detected by en-face optical coherence tomography images with custom slabs in eyes that underwent pars plana vitrectomy and SF6 for macula-on RRD.Main outcome measures were PAT area at baseline, 3-month and 6-month follow-up, and its relative change.
Near-infrared-II-driven Z-scheme heterojunction Polyglycolated MoS/CoFeO amplified edge potential for dual-mode imaging guided tumor synergistic therapy.
J Colloid Interface Sci
December 2024
School of Basic Medicine, General Hospital of Ningxia Medical University, Ningxia Medical University, Yinchuan 750004, China. Electronic address:
Targeting the peculiarities of tumor tissue microenvironment different from normal tissue, such as lower pH and overexpression of hydrogen peroxide is the key to effective treatment. In this study, acid-responsive Z-scheme heterojunctions polyglycolated MoS/CoFeO (MoS = molybdenum disulfide, CoFeO = cobalt ferrite) was synthesized using a two-step hydrothermal method, designated as MSCO-PEG, guided by dual modes of photoacoustic imagine (PAI) and nuclear magnetic imaging (MRI). MSCO-PEG (PEG = polyethylene glycol) responded to the acidic environment of tumor tissues and overexpression of hydrogen peroxide to turn on multimodal synergistic treatment of tumor cells under near-infrared-II (NIR-II) illumination.
View Article and Find Full Text PDFGadolinium oxide nanoparticles as a multimodal contrast enhancement agent for pre-clinical proton imaging.
Phys Med Biol
January 2025
Department of Medical Physics, Ludwig-Maximilians-Universität München, Am Coulombwall 1, Garching b. München, 85748, GERMANY.
Orthotopic tumor models in pre-clinical translational research are becoming increasingly popular, raising the demands on accurate tumor localization prior to irradiation. This task remains challenging both in X-ray and proton computed tomography (xCT and pCT, respectively), due to the limited contrast of tumor tissue compared to the surrounding tissue. We investigate the feasibility of gadolinium oxide nanoparticles as multimodal contrast enhancement agent for both imaging modalities.
View Article and Find Full Text PDFOptical Coherence Tomography Angiography findings in Syphilitic Outer Retinitis.
Retin Cases Brief Rep
December 2024
Department of Ophthalmology, Hospital de Clínicas, University of Buenos Aires, Buenos Aires, Argentina.
Purpose: to report optical coherence tomography angiography findings in syphilitic outer retinopathy, a singular clinical manifestation of ocular syphilis.
Methods: case report.
Results: Multimodal imaging including optical coherence tomography angiography was performed in a patient presenting syphilitic outer retinopathy.
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