We investigated the potential for waterless urinal sealants fluids to remove pharmaceuticals from urine. H NMR, FTIR, and GC/MS characterization of the fluids indicated that they are mostly composed of aliphatic compounds. Removal of ethinyl estradiol was >40% for two of the three sealant fluids during simulated urination to a urinal cartridge but removal of seven other compounds with greater hydrophilicity was <30%. At equilibrium with Milli-Q water, ≥ 89% partitioning to the sealant phase was observed for three compounds with pH adjusted log (log ) > 3.5. At equilibrium with synthetic urine, removal ranged widely from 2% to 100%. was poorly correlated with removal for both matrices at equilibrium, but was correlated with removal from synthetic urine for two of the three sealants, indicating that ionization and hydrophilicity control partitioning between the urine and sealant phases. To improve removal during urination, where equilibrium is not achieved, we increased the hydraulic retention time 100-fold over that of typical male urination. Removal of specific hydrophobic compounds increased, indicating that both hydrophobicity and kinetics control removal. Removal of ethinyl estradiol was ≥90% for all sealants in the increased hydraulic retention time experiment, demonstrating the potential for implementation to female urinals.
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http://dx.doi.org/10.1021/acs.est.9b06205 | DOI Listing |
Braz J Biol
January 2025
Embrapa Agrobiologia, Seropédica, RJ, Brasil.
The objective was to evaluate the sensitivity of Piptadenia gonoacantha seeds to desiccation and storage conditions. The seeds were subjected to artificial drying in a forced air convection oven (39.7 °C ± 0.
View Article and Find Full Text PDFLangmuir
January 2025
School of Nanoscience and Biotechnology, Shivaji University, Kolhapur, MH 416004, India.
In this study, we report the modification of a monolithic γ-aluminum oxy-hydroxide (γ-AlOOH) aerogel with cellulose nanofibers (CNFs) using the sol-gel method via supercritical drying. The optimized 2% CNF (w/w) results in a monolithic CNF-γ-AlOOH that is amorphous in nature, along with C-C and C-O-C functional groups. Transmission electron microscopy (TEM) images of the as-synthesized CNF-γ-AlOOH showed CNF embedded in the γ-AlOOH aerogel.
View Article and Find Full Text PDFSci Adv
January 2025
Division of Regenerative Medicine, Hartman Institute for Therapeutic Organ Regeneration, Ansary Stem Cell Institute, Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
Tissue-specific endothelial cells (ECs) are critical for the homeostasis of pancreatic islets and most other tissues. In vitro recapitulation of islet biology and therapeutic islet transplantation both require adequate vascularization, which remains a challenge. Using human reprogrammed vascular ECs (R-VECs), human islets were functionally vascularized in vitro, demonstrating responsive, dynamic glucose-stimulated insulin secretion and Ca influx.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
School of Materials Science & Engineering, The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University, Tianjin 300072, China.
Rib fracture-related infection is a challenging complication of thoracic trauma due to the difficulty of treating it with antibiotics alone and the need for a second operation to remove the infected fixator and sterilize the surrounding infected tissue. In this study, inspired by the photocatalytic performance of and ion release from silver-based materials, including AgPO and AgS, a hybrid AgPO-AgS heterojunction was prepared based on anion exchange and a one-step calcination process to design a nonantibiotic coating aimed at preventing and treating rib fracture-related infection with short-term 808 nm near-infrared irradiation. Calcination at 250 °C enhanced the inductive effect of the phosphate radical and led to the formation of a tight nanoheterogeneous interface between AgPO and AgS, thereby promoting interfacial electron transfer and reducing the recombination of photogenerated carriers.
View Article and Find Full Text PDFPLoS Genet
January 2025
Waksman Institute, Rutgers, the State University of New Jersey, Piscataway, New Jersey, United States of America.
Mitosis and meiosis have two mechanisms for regulating the accuracy of chromosome segregation: error correction and the spindle assembly checkpoint (SAC). We have investigated the function of several checkpoint proteins in meiosis I of Drosophila oocytes. Increased localization of several SAC proteins was found upon depolymerization of microtubules by colchicine.
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