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Where are we with fractionation schedules and prescriptions in high-dose-rate 3D planning vaginal cuff brachytherapy?
J Contemp Brachytherapy
October 2024
Fonaments Clinics Department, Universitat de Barcelona, Barcelona, Spain.
Purpose: Currently, there are many schedules for exclusive vaginal cuff brachytherapy (VCB). In 3D treatment planning for VCB dosimetry, parameters have not been analyzed. The aim of this study was to compare the most common schedules using dose-volume histogram metrics.
View Article and Find Full Text PDFFive-year results of a prospective trial of IORT-photon boost and hypofractionated whole-breast irradiation after breast-conserving surgery.
Clin Transl Oncol
December 2024
Centro Oncológico Integral Canario, Hospital Universitario San Roque, Las Palmas, Spain.
Aim: To assess for the first time the safety and feasibility of combining photon-IntraOperative RadioTherapy (ph-IORT) with hypofractionated whole-breast irradiation (hWBI) in patients referred to adjuvant radiotherapy after Breast-Conserving Surgery (BCS).
Methods: From February 2019 to August 2020, patients referred for breast-conserving surgery (BCS) in our institution were prospectively included in the present trial. BCS was discussed in the multidisciplinary tumor board (MTB).
Article Synopsis
- * The study involved five patients with inoperable tumors in different body locations, who received a total radiation dose of 51 Gy over 17 sessions, utilizing customized 3D-printed applicators.
- * All patients achieved complete remission based on the RTOG scale, and post-treatment evaluations showed restored skin structure and notable healing, indicating the effectiveness of the tailored brachytherapy approach.
Dosimetric evaluation of different cylinder diameters in three-dimensional vaginal brachytherapy for early-stage endometrial cancer.
J Cancer Res Clin Oncol
November 2024
Department of Radiation Oncology, Peking University Third Hospital, Beijing, 100191, China.
Purpose: To evaluate the dosimetric, radiobiological, and toxicity differences between different cylinder diameters (d) in high-dose-rate three-dimensional computed-tomography-guided vaginal brachytherapy (VBT) for early-stage endometrial cancer (EC).
Methods: From January 2019 to January 2024, postoperative EC patients treated with exclusive VBT using cylinders were classified by the cylinder diameter (d ≤ 2.6 cm: small-size; d ≥ 3.
A novel 3D printing method for a notched eye plaque "dummy" for uveal melanoma brachytherapy.
Brachytherapy
November 2024
Department of Radiation Oncology, Thomas Jefferson University Hospital, Philadelphia, PA; Ocular Oncology Service, Wills Eye Hospital, Philadelphia, PA.
Purpose: Suture preplacement by the ocular oncology surgeon is a critical step before inserting a radioactive plaque for ocular melanoma brachytherapy. We report on a novel 3D-printing method to create a custom "dummy" plaque applicator for the 22 mm notched gold plaque using in-house 3D-printing.
Methods: A computer-aided design (CAD) file was created replicating a heavily used gold plaque that no longer has a satisfactory "dummy" plaque.
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