[Research Progress on Regulating Autophagy in the Treatment of Multiple Myeloma --Review].

Zhongguo Shi Yan Xue Ye Xue Za Zhi

First Clinical Medical College of Fujian Medical University; Department of Hematology and Rheumatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, Fujian Province, China,E-mail:

Published: April 2020

Abstract  Autophagy is a process in which cells in eukaryotes degrades abnormal proteins and organelles, thus it possesses important effects on the survival of normal cells and tumor cells. The related studies have shown that autophagy is widely present in the life activities of myeloma cells, which not only protects myeloma cells, but also induces death, and plays an important role in survival, proliferation, invasion and migration of myeloma cells and the treatment of multiple myeloma. This review focuses on the progress of regulating autophagy in the treatment of multiple myeloma.

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http://dx.doi.org/10.19746/j.cnki.issn.1009-2137.2020.02.058DOI Listing

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