Jaw clonus, a fascinating, yet uncommon clinical sign, is suggestive of supranuclear lesions of the trigeminal nerve. It has previously been reported in association with amyotrophic lateral sclerosis. Hereby, we report an index case of jaw clonus in a patient of neuromyelitis optica spectrum disorder with subsequent osmotic demyelination syndrome with pseudobulbar palsy due to the involvement of pontine corticobulbar fibres.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114005 | PMC |
| http://dx.doi.org/10.4103/jfmpc.jfmpc_1117_19 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Rhythmic Jaw Movements in Amyotrophic Lateral Sclerosis: Is It Clonus or Tremor?
Tremor Other Hyperkinet Mov (N Y)
March 2024
Department of Neurology, Norman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, Florida, United States of America.
Background: Jaw clonus refers to involuntary, rhythmic jaw contractions induced by a hyperactive trigeminal nerve stretch reflex; however, the movements, when triggered without a stretch, can be confused with a tremor.
Phenomenology Shown: This video demonstrates a patient with amyotrophic lateral sclerosis presenting with rapid rhythmic jaw movements seen at rest, alongside a power spectrum analysis revealing a narrow high-frequency peak of 10 Hz.
Educational Value: Rhythmic jaw movements are seen in many disorders such as Parkinson's disease, essential tremor, tardive syndromes, and cranial myorhythmias; however, a high-frequency movement, regardless of clonus or tremor, can indicate amyotrophic lateral sclerosis when accompanied by typical upper and lower motor neuron signs.
Poisoning from Ingestion of Fungus-Infected Cicada Nymphs: Characteristics and Clinical Outcomes of Patients in Thailand.
Toxins (Basel)
December 2023
Ramathibodi Poison Center, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.
The current data regarding poisoning associated with ingestion of fungus-infected cicada nymphs are limited. We performed a retrospective cohort study of patients who ingested fungus-infected cicada nymphs and were referred to the Ramathibodi Poison Center for consultation from June 2010 to June 2022. Thirty-nine patients were included for analysis.
View Article and Find Full Text PDFTeaching Video NeuroImage: Disabling Jaw Clonus in a Patient With Bulbar-Onset Amyotrophic Lateral Sclerosis Successfully Treated With Botulinum Toxin.
Neurology
October 2022
From the Department of Neurosciences and Mental Health (M.O.S., M.S., A.V., M.d.C.), Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte; and Institute of Physiology (M.O.S., M.d.C.), Instituto de Medicina Molecular-JLA, Faculdade de Medicina, Universidade de Lisboa, Portugal.
Pearls & Oy-sters: Gait Instability, Jaw Dystonia, and Horizontal Diplopia in a Woman With Anti-Ri Antibodies and Breast Cancer.
Neurology
July 2022
From the Department of Clinical Neurological Sciences (S.A., Y.-C.C., A.B., J.M.R.), London Health Sciences Centre, Schulich Medicine and Dentistry, Western University; and Pathology and Laboratory Medicine (A.B.), Schulich Medicine and Dentistry, Western University, London, Ontario, Canada.
A 40-year-old woman was admitted for 6 months of progressive gait disturbance, lower limb-predominant weakness, stiffness, falls, jaw dystonia, horizontal diplopia, and weight loss. Neurologic examination revealed horizontal gaze paresis, limited jaw opening with palpable masseter hypertrophy, and spastic paraparesis with sustained clonus and upgoing plantar responses. MRI revealed T2-hyperintense signal abnormalities in the dorsal pons, medulla, and upper cervical cord central gray matter extending to C3, without gadolinium enhancement.
View Article and Find Full Text PDFRelapsing and Immune-Responsive Paroxysmal Jaw Clonus With Blepharospasm and Sialorrhea Associated With D2R Autoantibodies.
Neurol Neuroimmunol Neuroinflamm
July 2022
From the Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Objectives: To extend the symptomatic spectrum of acute neurologic syndrome associated with dopamine-2 receptor (D2R) antibodies.
Methods: A 13-year-old adolescent boy was admitted to the Neurology Department with abnormal jaw movements. The initial evaluation included laboratory examinations of blood, chest radiography, brain MRI, EEG, and neuropsychologic tests.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!