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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152974 | PMC |
| http://dx.doi.org/10.1155/2020/9586062 | DOI Listing |
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CMPK2 promotes NLRP3 inflammasome activation via mtDNA-STING pathway in house dust mite-induced allergic rhinitis.
Clin Transl Med
January 2025
Allergy Center, Department of Otolaryngology, Affiliated Eye and ENT Hospital, Fudan University, Shanghai, China.
Background: House dust mite (HDM) is the leading allergen for allergic rhinitis (AR). Although allergic sensitisation by inhaled allergens renders susceptible individuals prone to developing AR, the molecular mechanisms driving this process remain incompletely elucidated.
Objective: This study aimed to elucidate the molecular mechanisms underlying HDM-induced AR.
Reducing children's anxiety and pain in dental environment using an eye massage device combined with natural sounds-a randomized controlled trial.
Sci Rep
January 2025
Department of Pediatric Dentistry, Faculty of Dentistry, Damascus University, Damascus, Syria.
This study evaluated the efficacy of an eye massage device that uses acupressure points combined with natural sounds to reduce anxiety and pain in children receiving dental anesthesia for the first time. A total of 105 children aged between 8 and 10 years whose dental treatment required inferior alveolar nerve block (IANB) injection participated in this randomized controlled clinical trial. The participants were randomly divided into three groups: Group A: eye massage with natural sounds; Group B: eye massage only; and Group C (control group): traditional behavior management techniques.
View Article and Find Full Text PDFReduction in EEG theta power as a potential marker for spatial disorientation during flight.
Sci Rep
January 2025
Department of Cognitive and Brain Sciences, Ben-Gurion University of the Negev, 1 Ben-Gurion Blvd, Beer-Sheva, Israel.
During flight, spatial disorientation (SD) commonly occurs when a pilot's perception conflicts with the aircraft's actual motion, attitude, or position. A prevalent form of SD is the somatogyral illusion, which is elicited by constant speed rotation and causes a false perception of motion in the opposite direction when the rotation ceases. This research aimed to investigate changes in brain activity that occur when experiencing a somatogyral illusion by simulating conditions closely mimicking flight conditions to gain insight into how to better manage this illusion during flight.
View Article and Find Full Text PDFFaster referral and surgical intervention for rhegmatogenous retinal detachment during COVID-19: a comparison of pre- and during-pandemic cases.
Sci Rep
January 2025
Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Article Synopsis
- The study investigated how the COVID-19 pandemic affected patients with rhegmatogenous retinal detachment (RRD) at Farabi Eye Hospital in Iran, comparing patients from before and during the pandemic.
- A total of 375 patients were analyzed, revealing that those referred during the pandemic had quicker referral and surgical wait times, but no significant changes in clinical characteristics or surgical outcomes.
- The use of general anesthesia increased during the pandemic period, prompting the need for further research into this trend.
Blink completeness and rate in dry eye disease: An investigator-masked, prospective registry-based, cross-sectional, prognostic study.
Cont Lens Anterior Eye
January 2025
Department of Ophthalmology, Aotearoa New Zealand National Eye Centre, The University of Auckland, Auckland, New Zealand. Electronic address:
Purpose: To investigate the prognostic ability of blink rate and the proportion of incomplete blinking to predict dry eye disease diagnosis, as defined by the TFOS DEWS II criteria.
Methods: A total of 453 community residents (282 females, 171 males; mean ± SD age, 37 ± 19 years) were recruited in an investigator-masked, prospective registry-based, cross-sectional, prognostic study. Dry eye symptomology, tear film quality, and ocular surface characteristics were assessed in a single clinical session, and blink parameters evaluated by an independent masked observer.
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