Since March 2020, the COVID-19 pandemic has led to the need to re-think the delivery of services to patients with chronic dysimmune neuropathies. Telephone/video consultations have become widespread but have compounded concerns about objective evaluation. Therapeutic decisions need, more than ever before, to be considered in the best interests of both patients, and society, while not denying function-preserving/restoring treatment. Immunoglobulin therapy and plasma exchange, for those treated outside of the home, expose patients to the hazards of hospital or outpatient infusion centers. Steroid therapy initiation and continuation pose increased infectious risk. Immunosuppressant therapy similarly becomes highly problematic, with the risks of treatment continuation enhanced by uncertainties regarding duration of the pandemic. The required processes necessitate considerable time and effort especially as resources and staff are re-deployed to face the pandemic, but are essential for protecting this group of patients and as an integral part of wider public health actions.
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http://dx.doi.org/10.1002/mus.26896 | DOI Listing |
Rev Med Interne
September 2024
Service d'anatomopathologie, CHU de Brest, hôpital Morvan, Brest cedex, France; EA4685, LIEN, Inserm, universiyé de Brest, 29200 Brest, France.
Pract Neurol
August 2024
UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK
J Clin Apher
June 2024
Department of Nephrology-Dialysis-Apheresis, Nîmes University Hospital, Nîmes, France.
Background: The impact of chronic therapeutic plasmapheresis on humoral response following COVID-19 vaccination is poorly documented, especially among patients treated with double filtration plasmapheresis (DFPP).
Objectives: This retrospective single-center study evaluated the humoral response after SARS-CoV-2 vaccination and studied anti-SPIKE seropositivity and antibody dynamics in patients with chronic DFPP at our institution.
Method: All patients undergoing chronic DFPP at a tertiary center in France from December 2020 to November 2022 were included.
Curr Opin Allergy Clin Immunol
June 2024
Department of Medicine and Medical Therapeutics, University of Pavia.
Rev Neurol (Paris)
December 2024
Department of Neurology, University Hospital of Saint-Etienne, 42055 Saint-Étienne cedex, France. Electronic address:
Inflammatory sensory neuronopathies are rare disorders mediated by dysimmune mechanisms targeting sensory neurons in the dorsal root ganglia. They constitute a heterogeneous group of disorders with acute, subacute, or chronic courses, and occur with cancer, systemic autoimmune diseases, notably Sjögren syndrome, and viral infections but a noticeable proportion of them remains isolated. Identifying inflammatory sensory neuronopathies is crucial because they have the potential to be stabilized or even to improve with immunomodulatory or immunosuppressant treatments provided that the treatment is applied at an early stage of the disease, before a definitive degeneration of neurons.
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