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From Morphea to Dermatofibrosarcoma Protuberans.
Acta Dermatovenerol Croat
September 2022
Marija Delaš Aždajić, MD, PhD, Department of Dermatology and Venereology Sestre milosrdnice University Hospital Center, Vinogradska cesta 29 , 10 000 Zagreb , Croatia ;
Article Synopsis
- - Morphea profunda (MP) is a chronic autoimmune disease that leads to restricted skin movement and discomfort, while dermatofibrosarcoma protuberans (DFSP) is a rare, slowly growing tumor that can invade deeper tissues and has a tendency to recur locally but rarely spreads to other parts of the body.
- - A 39-year-old female patient had a brownish lesion diagnosed as MP at 20, which later developed into palpable nodules, leading to further evaluation and a new diagnosis of DFSP after deep biopsy and immunohistochemical analysis.
- - The patient underwent complete surgical removal of the DFSP tumor, followed by additional excision due to inadequate initial margins, and has shown no signs of
MORPHEA AND LICHEN SCLEROSUS IN A PATIENT WITH HYPORTHYROIDISM.
Acta Clin Croat
December 2020
Department of Dermatology, Silesian Medical University in Katowice, Katowice, Poland.
Thyroid gland is one of the key organs regulating the metabolism of carbohydrates, proteins and fats. Its primary function is connected with increase of the metabolic conversion of the body. Skin lesions are often one of the first symptoms of hypothyroidism.
View Article and Find Full Text PDFBrownish and Indurated Plaques With Yellowish Papules: Answer.
Am J Dermatopathol
May 2020
Department of Ophthalmology, University of Bonn, Bonn, Germany.
Treatment of primary cutaneous anaplastic large cell lymphoma.
Arch Craniofac Surg
June 2019
Department of Pathology, Dong-Kang General Hospital, Ulsan, Korea.
Primary cutaneous anaplastic large cell lymphoma (C-ALCL) is a rare subtype of primary cutaneous lymphoma with a favorable prognosis. Primary cutaneous CD30+ lymphoproliferative disorders, which include C-ALCL and lymphomatoid papulosis, are the second most common group of cutaneous T-cell lymphomas. C-ALCL is comprised of large cells with anaplastic, pleomorphic, or immunoblastic cytomorphology, and indeed, more than 75% of the tumor cells express the CD30 antigen.
View Article and Find Full Text PDFLichen Sclerosus on the Sites of Striae Distensae and a Surgical Scar in a Patient with Coexistent Morphea.
Acta Dermatovenerol Croat
March 2019
Sevkiye Copur, MD, Department of Dermatology & Venereology, Istanbul University, Istanbul Medical Faculty , Millet Street (Caddesi), 34093 Capa , Istanbul, Turkey;
Lichen sclerosus (LS), also known as lichen sclerosus et atrophicus, is a chronic inflammatory mucocutaneous disease affecting the genital and/or extragenital areas. Although LS usually occurs alone, its coexistence in morphea patients has been reported in 5.7% and 38.
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