Metastases from pancreatic malignancy are commonly known to occur in the regional lymph nodes, liver, lung, and peritoneum. Synchronous or metachronous metastasis from the pancreas to the colon is rare, with only 6 cases reported in the literature. We report a man who was found to have adenocarcinoma on biopsies from synchronous lesions in the colon and the pancreas. The immunohistochemistry report revealed the diagnosis of a primary pancreatic malignancy with synchronous colonic metastases.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145160PMC
http://dx.doi.org/10.14309/crj.0000000000000299DOI Listing

Publication Analysis

Top Keywords

synchronous colonic
8
colonic metastases
8
pancreatic malignancy
8
pancreatic adenocarcinoma
4
synchronous
4
adenocarcinoma synchronous
4
metastases metastases
4
metastases pancreatic
4
malignancy commonly
4
commonly occur
4

Similar Publications

An RNase III-processed sRNA coordinates sialic acid metabolism of during gut colonization.

Proc Natl Acad Sci U S A

January 2025

Key Laboratory of Medical Molecular Virology (Ministry of Education / National Health Commission / Chinese Academy of Medical Sciences), Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai 200033, China.

Sialic acids derived from colonic mucin glycans are crucial nutrients for enteric bacterial pathogens like . The uptake and utilization of sialic acid in depend on coordinated regulons, each activated by specific metabolites at the transcriptional level. However, the mechanisms enabling crosstalk among these regulatory circuits to synchronize gene expression remain poorly understood.

View Article and Find Full Text PDF

Background: The treatment of locally recurrent rectal cancer has evolved dramatically in recent decades. As the boundaries of exenterative surgery continue to be pushed, one of the unanswered and controversial questions is the role of radical salvage surgery for locally recurrent rectal cancer in the setting of oligometastatic disease.

Objective: To investigate the impact of synchronous or previously treated distant metastases on survival following pelvic exenteration for locally recurrent rectal cancer.

View Article and Find Full Text PDF

SYNCHRONOUS COLON CANCER ASSOCIATED WITH IDIOPATHIC THROMBOCYTOPENIC PURPURA. CLINICAL CASE.

Probl Radiac Med Radiobiol

December 2024

State Institution «National Research Center for Radiation Medicine, Hematology and Oncology of the National Academy of Medical Sciences of Ukraine», 53 Yuriia Illienka Str., Kyiv, 04050, Ukraine.

We present а rare clinical case of successful surgical treatment - combined left-sided hemicolectomy and cecal resection for colon cancer of two locations in a patient with idiopathic thrombocytopenic purpura, which, in our opinion, is due to radiation exposure is presented. It is shown that the biological effects of long-term ionizing radiation on critical organs can have a diverse nature both in terms of the time of occurrence and in their structure, which requires an individual approach, the involvement of related specialists and the necessary medical preoperative preparation for precise planning of surgical intervention taking into account all possible risks.

View Article and Find Full Text PDF

Colon lipomas are rare benign, nonepithelial tumors that are often asymptomatic. However, when symptoms do occur, they vary depending on the size and location of the lipoma and are generally nonspecific. Diagnosis is confirmed through histopathological analysis.

View Article and Find Full Text PDF

The chemotactic response of Caenorhabditis elegans represents a promising tool for the early detection of cancer.

Discov Oncol

December 2024

Department of Laboratory Medicine, Faculty of Health Care and Social Work, Trnava University in Trnava, Univerzitné Námestie 1, 91843, Trnava, Slovakia.

Article Synopsis
  • Caenorhabditis elegans is being explored as a tool for chemotaxis testing due to its sensitive olfactory system, especially in cancer diagnostics.
  • This study aimed to assess the nematode's ability to differentiate between urine samples from healthy individuals and those with breast or colon cancer.
  • Results indicated a significant difference in the nematodes' responses, with high diagnostic sensitivity (96% for breast cancer, 100% for colon cancer) and moderate specificity (62%) in detecting cancer through urinary volatile organic compounds.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!