Buspirone for the Management of Functional Dyspepsia With Rapid Gastric Emptying.

ACG Case Rep J

Department of Gastroenterology, Hepatology, & Nutrition Cleveland Clinic, Cleveland, OH.

Published: November 2019

Functional dyspepsia is characterized by a constellation of upper gastrointestinal symptoms consisting of epigastric pain and burning, early satiety, and postprandial fullness-all in the absence of any explanatory organic gastrointestinal pathology. Treatment options for the condition are limited, in part, because of the incomplete understanding of the pathophysiology of the disorder. A subset of patients diagnosed with functional dyspepsia are subsequently found to have rapid gastric emptying on gastric emptying scintigraphy. The significance of this finding is unknown but provides a potential therapeutic target. This case report describes functional dyspepsia with rapid gastric emptying responsive to treatment with buspirone.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145204PMC
http://dx.doi.org/10.14309/crj.0000000000000280DOI Listing

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