Plasma-cell gingivitis (PCG) is an uncommon inflammatory condition of idiopathic etiology. PCG is a rare condition, appearing as erythema (redness) and edema (swelling) of the attached gingiva. The diagnosis of PCG is based on arrant history taking, clinical examination, and appropriate diagnostic tests. Here, we are presenting a case of PCG in a 12-year-old boy, its management and treatment outcome after 3 years of regular follow-up in tertiary health-care center in North Kerala.
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http://dx.doi.org/10.4103/ccd.ccd_776_18 | DOI Listing |
Cells
November 2024
Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Bucharest, 91-95 Spl. Independentei, 050657 Bucharest, Romania.
Due to its antimicrobial, anti-inflammatory and pro-healing properties, the application of cold atmospheric plasma (CAP) has emerged as a new and promising therapeutic strategy in various fields of medicine, including general medicine and dentistry. In this light, the aim of the present study was to investigate the effects of a homemade plasma jet on the cellular behaviour of two important cell types involved in gingivitis, namely gingival fibroblasts (HGF-1 cell line) and macrophages (RAW 264.7 cell line), by the direct application of CAP in different experimental conditions.
View Article and Find Full Text PDFCytotechnology
February 2025
Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090 Russia.
The development of new compounds or materials for medicine suggests a study of their cytotoxicity. The effect of a material on cell viability can be evaluated by several methods based on DNA content, DNA synthesis, plasma membrane integrity, cellular enzyme activity, cellular reducing potential, and ATP level. Sometimes it is impossible to apply widely used commercially available reagents, e.
View Article and Find Full Text PDFJ Periodontal Res
November 2024
Department of Physiology and Pathology, School of Dentistry, São Paulo State University (UNESP), Araraquara, Brazil.
Aims: Chronic periodontitis is the sixth most prevalent disease worldwide and the leading cause of tooth loss in adults. With growing attention on the role of inflammatory and immune responses in its pathogenesis, there is an urgent need to evaluate host-modulatory agents. Non-steroidal anti-inflammatory drugs (NSAIDs) drugs play a crucial role in managing inflammatory conditions.
View Article and Find Full Text PDFCureus
October 2024
Department of Periodontology and Dental Implantology, Medical University of Varna, Varna, BGR.
Context The underlying principle of guided tissue regeneration (GTR) lies in the use of barrier membranes. Their role is key to this method, as they inhibit the rapid growth of epithelial and connective tissue cells, thus isolating the infrabony defects (IBDs) and ensuring the regeneration of slower-growing periodontal structures. The main disadvantages of resorbable membranes are related to their limited time of action and the need to use them in two layers, which increases the chance of a postoperative complication, i.
View Article and Find Full Text PDFOrthod Craniofac Res
November 2024
Department of Orthodontics, Peking University School and Hospital of Stomatology, Beijing, People's Republic of China.
Aim: To examine the immune responses in patients diagnosed as grade C periodontitis during orthodontic treatment.
Materials And Methods: Our study included seven orthodontic patients with grade C periodontitis and measured their levels of inflammatory cytokines in gingival crevicular fluid and plasma before orthodontic treatment, during the alignment and levelling phase, and during the detailing and finishing phase. The key signal pathways in the orthodontic process of patients with periodontitis were detected by KEGG analysis.
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