It is known that beta-catenin is associated with fibromatosis, sarcoma and mesenchymal tumor. Therefore, it is of interest to design an effective inhibtitor to the target protein beta-catenin. In this study, we report the molecular docking analysis of alkaloid compounds (aristolochicacid, cryptopleurine, demecolcine, fagaronine and thalicarpine) with beta-catenin for further consideration towards the design and development of potential inhintors for the treatmnet of colon cancer.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147492 | PMC |
| http://dx.doi.org/10.6026/97320630016283 | DOI Listing |
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